2′-氨基苯乙酮 盐酸盐合成路线 （共 16 条）
反应条件
hydrogenchloride in 1,4-dioxane; diethyl ether
参考文献
Organic Letters, , vol. 14, # 1 p. 288 - 291
反应条件
hydrogenchloride; tin(ll) chloride in ethanol; water T=30°C; Rate constantMechanism;
参考文献
Journal of Organic Chemistry, , vol. 47, # 18 p. 3577 - 3581
参考文献
Japan Tobacco Inc.
Patent: EP885869 A1, 1998 ;
反应条件
in neat (no solvent) T=140°C; 0.5 h;
参考文献
Jacquignon; Croisy; Ricci; Balucani
1973 , vol. 38, # 12 p. 3862 - 3871
反应条件
in neat (no solvent) T=140°C; 0.5 h;
参考文献
Jacquignon; Croisy; Ricci; Balucani
1973 , vol. 38, # 12 p. 3862 - 3871
反应条件
1: 94 percent / NH2OH*HCl / aq. ethanol / 264 h / Ambient temperature
2: 91 percent / acetic acid / 0.17 h / 50 °C
3: 77 percent / methanol / 72 h / Ambient temperature
View Scheme
参考文献
Lessel
Archiv der Pharmazie, 1994 , vol. 327, # 2 p. 77 - 84
参考文献
Theiling; McKee
Journal of the American Chemical Society, 1952 , vol. 74, p. 1834
反应条件
potassium carbonate in water; ethyl acetate
T=0 - 30°C; 3.5 h;
参考文献
KYOWA HAKKO KOGYO CO., LTD.; Fujifilm Corporation
Patent: EP1870404 A1, 2007 ;
Location in patent: Page/Page column 37 ;
反应条件
1: 94 percent / NH2OH*HCl / aq. ethanol / 264 h / Ambient temperature
2: 91 percent / acetic acid / 0.17 h / 50 °C
View Scheme
参考文献
Lessel
Archiv der Pharmazie, 1994 , vol. 327, # 2 p. 77 - 84
反应条件
1: 84 percent / 0.17 h / 140 °C
2: 71 percent / 5percent Pd/C / Heating
3: 81 percent / pyridinium chloride / 0.25 h / Heating
4: 94 percent / 5percent aq. NaOH / 0 °C
View Scheme
参考文献
Croisy Delcey; Croisy; Zajdela; Lhoste
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 303 - 306
