4'-(咪唑-1-基)苯腈合成路线 （共 15 条）
反应条件
copper(l) iodide; caesium carbonate in N,N-dimethyl-formamide T=120°C; 40 h;
参考文献
Journal of Organic Chemistry, , vol. 72, # 22 p. 8535 - 8538
反应条件
potassium carbonate; trans-1,2-diaminocyclohexane-based copper(II) complex in N,N-dimethyl-formamide T=110°C; 1 h;
参考文献
Kantam, M. Lakshmi; Ramani; Chakrapani
Synthetic Communications, 2008 , vol. 38, # 4 p. 626 - 636
反应条件
potassium carbonate in N,N-dimethyl-formamide T=120°C; 6 h;
参考文献
Sreedhar; Arundhathi; Linga Reddy; Amarnath Reddy; Lakshmi Kantam
Synthesis, 2009 , # 15 art. no. P03909SS, p. 2517 - 2522
反应条件
copper(l) iodide; caesium carbonate; N,N-dimethylimidodicarbonimidic diamide in N,N-dimethyl-formamide T=20 - 110°C; Ullmann Condensation; 8.16667 h;
参考文献
Ghorbani-Vaghei, Ramin; Hemmati, Saba; Veisi, Hojat
Tetrahedron Letters, 2013 , vol. 54, # 52 p. 7095 - 7099
反应条件
2Na(1+)*CuC6H4(NCHC6H3OO3S)2(2-)=CuC6H4(NCHC6H3ONaO3S)2 in water T=100°C; 6 h;
参考文献
Wang, Lixia; Jiang, Zhaoqiong; Yu, Lintao; Li, Lili; Li, Zhengkai; Zhou, Xiangge
Chemistry Letters, 2010 , vol. 39, # 7 p. 764 - 765
反应条件
1: 4-fluorobenzenecarbonitrile With cesium fluoride in N,N-dimethyl-formamide 0.166667 h; Inert atmosphere; 2: N-(trimethylsilyl)-imidazole in N,N-dimethyl-formamide T=60°C; 20 h;
参考文献
Zylum Beteiligungsgesellschaft mbH and Co. Patente II KG
Patent: US2012/142937 A1, 2012 ;
Location in patent: Page/Page column 5 ;
反应条件
in DMF (N,N-dimethyl-formamide) T=80°C; 12 h;
参考文献
SCHERING CORPORATION; PHARMACOPEIA, INC.
Patent: WO2004/22561 A1, 2004 ;
Location in patent: Page 100 ;
WO 2004/022561 A1
反应条件
cesium fluoride in N,N-dimethyl-formamide T=60°C; 20 h; Inert atmosphere;
参考文献
Dehe, Daniel; Munstein, Isabel; Reis, Andreas; Thiel, Werner R.
Journal of Organic Chemistry, 2011 , vol. 76, # 4 p. 1151 - 1154
反应条件
in N,N-dimethyl-formamide
参考文献
US2004/209878 A1, ;
US 20040209878 A1
反应条件
in dimethyl sulfoxide
