N,N-二boc-2-氯-4-氨基苯胺合成路线 （共 3 条）
反应条件
iron; acetic acid in methanol 0.5 h; Heating;
参考文献
Tsou, Hwei-Ru; Overbeek-Klumpers, Elsebe G.; Hallett, William A.; Reich, Marvin F.; Floyd, M. Brawner; Johnson, Bernard D.; Michalak, Ronald S.; Nilakantan, Ramaswamy; Discafani, Carolyn; Golas, Jonathan; Rabindran, Sridhar K.; Shen, Ru; Shi, Xiaoqing; Wang, Yu-Fen; Upeslacis, Janis; Wissner, Allan
Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 1107 - 1131
反应条件
1: 100 percent / DMAP / tetrahydrofuran / 3 h / 25 °C 2: 100 percent / iron; AcOH / methanol / 0.5 h / Heating View Scheme
参考文献
Vanderbilt University
Patent: US2011/124663 A1, 2011 ;
US 20110124663 A1
反应条件
1: 4-(N,N-dimethlyamino)pyridine / tetrahydrofuran / 16 h / 20 °C 2: hydrogen / ethyl acetate / 16 h / 760.05 Torr View Scheme
参考文献
Tsou, Hwei-Ru; Overbeek-Klumpers, Elsebe G.; Hallett, William A.; Reich, Marvin F.; Floyd, M. Brawner; Johnson, Bernard D.; Michalak, Ronald S.; Nilakantan, Ramaswamy; Discafani, Carolyn; Golas, Jonathan; Rabindran, Sridhar K.; Shen, Ru; Shi, Xiaoqing; Wang, Yu-Fen; Upeslacis, Janis; Wissner, Allan
Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 1107 - 1131
