1-(4-氨丁基)胍硫酸盐合成路线 （共 5 条）
参考文献
DE463576 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2510
参考文献
DE463576 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2510
反应条件
hydrogenchloride; sodium hydroxide 1) water, ethanol, reflux, cca. 20 h; 2) r.t.; Yield given. Multistep reaction;
参考文献
Richards, James C.; Spenser, Ian D.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 2810 - 2820
反应条件
1: 4-aminobutylguanidine sulfate With potassium carbonate in water T=0 - 5°C; 0.166667 h; 2: acryloyl chloride in water; acetone T=5°C; 1 h; 3: With sulfuric acid; potassium carbonate Product distribution / selectivity; more than 3 stages;
参考文献
AMERSHAM BIOSCIENCES AB
Patent: WO2005/40092 A1, 2005 ;
Location in patent: Page/Page column 8 ;
反应条件
tetreamethyl ammonium hydroxide in methanol 1 h;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Patent: EP1491217 A1, 2004 ;
Location in patent: Page 6 ;
