2-(三苯基正膦基)丙醛合成路线 （共 20 条）
反应条件
1: (ethyl)-triphenylphosphonium iodide With n-butyllithium in tetrahydrofuran; toluene T=22°C; Dehydroiodination; 1 h; 2: formic acid ethyl ester With potassium tert-butylate in tetrahydrofuran; toluene T=0°C; Formylation; 0.25 h;
参考文献
Kiyooka, Syun-Ichi; Hena, Mostofa A.
Journal of Organic Chemistry, 1999 , vol. 64, # 15 p. 5511 - 5523
反应条件
in 1,2-dichloro-ethane Under N2 a soln. of Pd(CNC6H4OCH3)(Ch3C3H4)(Ph3PC(H)COCH3) in 1,2-dichloroethane is treated with CNC6H4OCH3, mixt. is stirred for 30 min at room temp.; Taken to dryness under reduced pressure, residue extd. with C6H6, insoluble compound is filtered off, washed with Et2O, elem. anal.;
参考文献
Facchin, Giacomo; Bertani, Roberta; Zanotto, Livio; Calligaris, Mario; Nardin, Giorgio
Journal of Organometallic Chemistry, 1989 , vol. 366, p. 409 - 420
反应条件
1: 75 percent / benzene 2: 1) 2 N H2SO4, 2) 0.5 N NaOH / 1) H2O, 30 min, 2) H2O View Scheme
参考文献
Chemische Berichte, , vol. 117, # 4 p. 1561 - 1571
反应条件
1: NaNH2, liq. NH3 2: 75 percent / benzene 3: 1) 2 N H2SO4, 2) 0.5 N NaOH / 1) H2O, 30 min, 2) H2O View Scheme
参考文献
Chemische Berichte, , vol. 117, # 4 p. 1561 - 1571
参考文献
Tetrahedron Letters, , vol. 33, # 7 p. 861 - 864
反应条件
sodium hydroxide; sulfuric acid 1) H2O, 30 min, 2) H2O; Yield given. Multistep reaction;
参考文献
Chemische Berichte, , vol. 117, # 4 p. 1561 - 1571
参考文献
Givaudan Corporation
Patent: US3935275 A1, 1976 ;
反应条件
butane-1-thiol; sodium hydride; mercuric sulphate 1.) CH2Cl2, reflux, 24h, 2.) ether, room temp., 24h, reflux, 24h, 3.) 1h; Yield given. Multistep reaction;
参考文献
Garst, Michael E.; Spencer, Thomas A.
Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2442 - 2443
反应条件
in tetrahydrofuran; water Wittig reaction;
参考文献
Lengkeek, Nigel A.; Greenwood, Paul F.; Nguyen, Blake; Koutsantonis, George A.; Piggott, Matthew J.
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 1 p. 141 - 150
反应条件
in tetrahydrofuran 16 h; Reflux;
参考文献
Bergonzini, Giulia; Vera, Silvia; Melchiorre, Paolo
Angewandte Chemie - International Edition, 2010 , vol. 49, # 50 p. 9685 - 9688
