1.1: 95 percent / PdCl2(PPh3)2 / toluene / 2 h / Heating 2.1: O3 / CH2Cl2 / -78 °C 2.2: 85 percent / Me2S / -78 °C 3.1: 95 percent / aq. HCl / methanol / 24 h / 90 °C / Heating View Scheme

TEA; bis (triortho-tolylphosphine)palladium(II) chloride in N,N-dimethyl-formamide Heck coupling; Heating;