1.1: diisopropylamine; n-butyllithium; DMPU / tetrahydrofuran; hexane / 1 h / -78 °C 1.2: 52 percent / tetrahydrofuran; hexane / -78 - 20 °C 2.1: NaOH; hydroxylamine hydrochloride; acetic acid / methanol / 72 h / 20 °C 2.2: 81 percent / trifluoroacetic acid; water / CH2Cl2 / 48 h / 20 °C View Scheme