1,3-二氢-2-苯并噻吩 2,2-二氧化物合成路线 （共 27 条）
反应条件
1: 70 percent / AgSO4, I2 / H2SO4 / 16 h / 20 °C 2: 68 percent / alumina, Pd(PPh3)4 / toluene / 3 h / 100 °C 3: 82 percent / NaH / tetrahydrofuran; hexamethylphosphoric acid triamide / 12 h / -30 - 20 °C 4: 80 percent / various solvent(s) / 3 h / 213 °C 5: 93 percent / diethyl ether / 0.08 h / -20 °C 6: CF3CO3H / CH2Cl2 / 1 h / 20 °C 7: 2N HCl / methanol; tetrahydrofuran / 3 h / 60 °C View Scheme
参考文献
Oppolzer, Wolfgang; Roberts, David Anthony
Helvetica Chimica Acta, 1980 , vol. 63, # 6 p. 1703 - 1705
参考文献
Cava; Deana
Journal of the American Chemical Society, 1959 , vol. 81, p. 4266
反应条件
1: 70 percent / various solvent(s) / 18 h / Heating 2: 11 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone; dioxane / 48 h / Heating View Scheme
参考文献
Brito, Cristela M.; Pinto, Diana C. G. A.; Silva, Artur M. S.; Silva, Ana M. G.; Tome, Augusto C.; Cavaleiro, Jose A. S.
European Journal of Organic Chemistry, 2006 , # 11 p. 2558 - 2569
反应条件
aluminium trichloride in various solvent(s) Diels-Alder reaction; 14 h; Heating;
参考文献
Sandulache, Angela; Silva, Artur M.S; Cavaleiro, Jose A.S
Tetrahedron, 2002 , vol. 58, # 1 p. 105 - 114
反应条件
in various solvent(s) Diels-Alder reaction; 72 h; Heating;
参考文献
Sandulache, Angela; Silva, Artur M.S; Cavaleiro, Jose A.S
Tetrahedron, 2002 , vol. 58, # 1 p. 105 - 114
反应条件
1: 61 percent / 1 h / 280 - 285 °C 2: 84 percent / S / tetrahydrothiophene 1,1-dioxide / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 33, # 1 p. 109 - 111
反应条件
T=460 - 770°C; unter Stickstoff.Pyrolysis;
参考文献
Schiess, Peter; Rutschmann, Suzanne; Toan, Van Vien
Tetrahedron Letters, 1982 , vol. 23, # 36 p. 3665 - 3668
参考文献
Cava; Deana
Journal of the American Chemical Society, 1959 , vol. 81, p. 4266
反应条件
peroxypropionic acid in acetic acid
2) rt, 24 h;
参考文献
Neidlein, Richard; Doerr, Henning
Liebigs Annalen der Chemie, 1980 , # 10 p. 1540 - 1548
反应条件
sulfur dioxide; hydroxymethanesulfinic acid sodium salt in N,N-dimethyl-formamide
T=70°C; 11 h;
参考文献
Hoey, Michael D.; Dittmer, Donald C.
Journal of Organic Chemistry, 1991 , vol. 56, # 5 p. 1947 - 1948
