T=20°C; Solid phase reaction; condensation; 0.5 h;

1: 5,5-dimethyl-3-methoxy-2-cyclohexene-1-one With oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane T=0°C; Inert atmosphere; 2: 4-methoxy-aniline With triethylamine in dichloromethane T=0 - 20°C;

tris(dibenzylideneacetone)dipalladium (0); caesium carbonate; N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine in tetrahydrofuran T=80°C; Arylation; Heck reaction; 20 h;

1: 82 percent / toluene / 24 h / 20 °C 2: 30 percent / acetic acid / 10 h / Heating View Scheme

acetic acid 10 h; Heating;