1,2,4-噁二唑啉-3,5-二酮合成路线 （共 8 条）
反应条件
sodium hydroxide in ethanol T=60°C; 0.5 h;
参考文献
Zinner; Menzel; Sunderdiek; Fischer
Archiv der Pharmazie, 1981 , vol. 314, # 4 p. 294 - 302
反应条件
boron tribromide in dichloromethane 1) -50 deg C, 30 min, 2) to r.t. for 4 h, 3) -18 deg C, 20 h;
参考文献
Renaut; Thomas; Bellamy
Synthesis, 1991 , # 4 p. 265 - 266
反应条件
potassium hydroxide 0.0833333 h; Heating;
参考文献
Srivastava, Prem C.; Robins, Roland K.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1172 - 1177
反应条件
gallium Nitrate; pyridoxal 5'-phosphate in water T=62 - 65°C; 2 h; pH=5.0;
参考文献
Murakoshi, Isamu; Ikegami, Fumio; Yoneda, Yoshihiro; Ihara, Harumi; Sakata, Kumiko; Koide, Chiharu
Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1473 - 1478
反应条件
Tris-HCl buffer T=30°C; 0.166667 h; β-cyano-L-alanine synthase (from Spinacia oleracea, Chenopodiaceae);
参考文献
Ikegami, Fumio; Takayama, Kyoko; Tajima, Chiho; Murakoshi, Isamu
Phytochemistry (Elsevier), 1988 , vol. 27, # 7 p. 2011 - 2016
反应条件
acetate buffer; metal ions; pyridoxal 5'-phosphate
参考文献
Murakoshi, Isamu; Ikegami, Fumio; Koide, Chiharu
Heterocycles, 1984 , vol. 21, # 2 p. 705
反应条件
triethylamine in pyridine
参考文献
Evans; Francis; Hunt; Martin; Watkins
Journal of Pharmacy and Pharmacology, 1978 , vol. 30, # 6 p. 364 - 367
反应条件
in methanol; diethyl ether; water
参考文献
Zinner,G.; Stoffel,R.
Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1969 , vol. 302, p. 691 - 694
