异烟酸甲酯合成路线

2459-09-8异烟酸甲酯→94413-69-12-(氨基甲基)异烟酸甲酯盐酸盐

参考文献

GENENTECH,INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Kanl H.; DRAGOVICH, Peter; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; YUEN, Po-Wai; ZAK, Mark; ZHANG, Yamin; ZHENG, Xiaozhang; ZHAO, Guiling
Patent: WO2013/127268 A1, 2013 ;

2459-09-8异烟酸甲酯→94413-64-62-氰基-4-吡啶羧酸甲酯

参考文献

GENENTECH,INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Kanl H.; DRAGOVICH, Peter; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; YUEN, Po-Wai; ZAK, Mark; ZHANG, Yamin; ZHENG, Xiaozhang; ZHAO, Guiling
Patent: WO2013/127268 A1, 2013 ;

2459-09-8异烟酸甲酯→91912-53-75-(4-吡啶基)-1H-吡唑-3-胺

参考文献

Journal of Medicinal Chemistry, , vol. 55, # 10 p. 4806 - 4823

2459-09-8异烟酸甲酯→20691-91-21-(1-甲基-4-哌啶基)-乙酮

参考文献

Grob; Renk
Helvetica Chimica Acta, 1954 , vol. 37, p. 1672,1676

2459-09-8异烟酸甲酯+94-36-0过氧化苯甲酰→93-99-2苯甲酸苯酯+92-52-4联苯+4634-14-42-苯基吡啶-4-羧酸甲酯+850162-87-73-苯基-4-吡啶羧酸甲酯+65-85-0苯甲酸

参考文献

Court, J.; Vidal, S.; Bonnier, J. M.
Tetrahedron, 1988 , vol. 44, # 21 p. 6623 - 6632

2459-09-8异烟酸甲酯→23714-52-54-环己基-5-吡啶-4-基-4H-[1,2,4]噻唑-3-硫醇

参考文献

Romaine, Ian M.; Taylor, Robert W.; Saidu, Samsudeen P.; Kim, Kwangho; Sulikowski, Gary A.; Zwiebel, Laurence J.; Waterson, Alex G.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 12 p. 2613 - 2616

2459-09-8异烟酸甲酯→89937-77-92-羟基砒啶-4-羧酸甲酯

参考文献

Allied-Signal Inc.
Patent: US4968803 A1, 1990 ;

2459-09-8异烟酸甲酯→100-48-14-氰基吡啶

参考文献

Camps
Archiv der Pharmazie (Weinheim, Germany), 1902 , vol. 240, p. 358

2459-09-8异烟酸甲酯→80845-58-51-苄基-1,2,3,6-四氢吡啶-4-羧酸甲酯

参考文献

Journal of Organic Chemistry, , vol. 47, # 12 p. 2435 - 2440

2459-09-8异烟酸甲酯+119329-92-9→119-65-3异喹啉

参考文献

Journal of the American Chemical Society, , vol. 109, # 10 p. 3040 - 3046