4-羟基-5-甲氧基-2-硝基苯甲醛合成路线 （共 18 条）
反应条件
hydrogen bromide in acetic acid T=85°C; 1 h;
参考文献
Tsai, Shiou-Chuan; Klinman, Judith P.
Bioorganic Chemistry, 2003 , vol. 31, # 2 p. 172 - 190
反应条件
sodium in methanol; dimethyl sulfoxide T=150°C; 0.0583333 h;
参考文献
Imakura; Okimoto; Konishi; Hisazumi; Yamazaki; Kobayashi; Yamashita
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 7 p. 1691 - 1696
反应条件
nitrogen(IV) oxide P=225.02 Torr; 12 h;
参考文献
Kaupp, Gerd; Schmeyers, Jens
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5494 - 5503
反应条件
(i) NO2/HNO3, (ii) H2SO4; Multistep reaction;
参考文献
Rogers, C. Bradford; Blum, Charles A.; Murphy, Bryan P.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 941 - 943
反应条件
in methanol; dimethyl sulfoxide; N,N-dimethyl-formamide T=150°C; 2 h;
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
sodium methylate in methanol; dimethyl sulfoxide T=150°C;
参考文献
Kobayashi; Kihara; Yamahara
Chemical and Pharmaceutical Bulletin, 1978 , vol. 26, # 10 p. 3113 - 3116
反应条件
1: K2CO3; acetone 2: water; nitric acid / 0 °C 3: concentrated sulfuric acid / 50 - 60 °C View Scheme
参考文献
Tsai, Shiou-Chuan; Klinman, Judith P.
Bioorganic Chemistry, 2003 , vol. 31, # 2 p. 172 - 190
反应条件
sulfuric acid T=50 - 60°C;
参考文献
Nair; Robinson
Journal of the Chemical Society, 1932 , p. 1236,1238
反应条件
sulfuric acid T=50 - 60°C;
参考文献
Nair; Robinson
Journal of the Chemical Society, 1932 , p. 1236,1238
参考文献
Teague, Simon J.
Tetrahedron Letters, 1996 , vol. 37, # 32 p. 5751 - 5754
