N-(2-溴-6-硝基-苯基)-乙酰胺合成路线 （共 8 条）
反应条件
nitric acid; trifluoroacetic acid in water T=20 - 50°C;
参考文献
TARGEGEN INC.
Patent: WO2009/55674 A1, 2009 ;
Location in patent: Page/Page column 82 ;
WO 2009/055674 A1
反应条件
1: With nitric acid T=0°C; 2: With sodium hydrogencarbonate in water pH=7;
参考文献
Samumed, LLC; Hood, John; Kumar KC, Sunil; Wallace, David Mark
Patent: US2013/296302 A1, 2013 ;
Location in patent: Paragraph 0587 ;
反应条件
nitric acid in acetic anhydride
参考文献
Cho, Gae Young; Remy, Pauline; Jansson, Jenny; Moessner, Christian; Bolm, Carsten
Organic Letters, 2004 , vol. 6, # 19 p. 3293 - 3296
反应条件
sulfuric acid; nitric acid T=20°C; 7 h;
参考文献
Wepster; Verkade
Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 88,89
反应条件
nitric acid; acetic anhydride; acetic acid Behandeln des Reaktionsprodukts mit wss.-aethanol.Kalilauge;
参考文献
Wepster; Verkade
Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 88,89
参考文献
Franzen; Engel
Journal fuer Praktische Chemie (Leipzig), 1921 , vol. <2>102, p. 184
参考文献
GLAXO GROUP LIMITED; CHAMBERS, Laura Jane; DEAN, David Kenneth; MUNOZ-MURIEDAS, Jorge; STEADMAN, Jon Graham Anthony; WALTER, Daryl Simon
Patent: WO2010/125103 A1, 2010 ;
Location in patent: Page/Page column 78 ;
WO 2010/125103 A1
反应条件
1: N-(2-bromo-6-nitro-phenyl)-acetamide With potassium hexamethylsilazane in N,N-dimethyl-formamide T=20°C; 0.166667 h; 2: isopropyl bromide in N,N-dimethyl-formamide T=60°C;
参考文献
WO2009/55674 A1, ;
Page/Page column 82-83 ;
WO 2009/055674 A1
