2,4-二甲基吡咯-3,5-二羧酸二乙酯合成路线 （共 64 条）
反应条件
bromine in tetrachloromethane
T=30°C; effect of light; var. molar ratio Br2:pyrrole; MechanismKineticsProduct distribution;
参考文献
Angelini, Giancarlo; Giancaspro, Carlo; Illuminati, Gabriello; Sleiter, Giancarlo
Journal of Organic Chemistry, 1980 , vol. 45, # 10 p. 1786 - 1790
反应条件
bromine; acetic acid; Petroleum ether
参考文献
Treibs; Bader
Justus Liebigs Annalen der Chemie, 1959 , vol. 627, p. 182,192
参考文献
Fischer; Schormueller
Justus Liebigs Annalen der Chemie, 1929 , vol. 473, p. 211,234
Full Text Show Details
Fischer; Halbig
Justus Liebigs Annalen der Chemie, 1926 , vol. 447, p. 126,137
Justus Liebigs Annalen der Chemie, 1926 , vol. 448, p. 199
反应条件
1: glacial acetic acid; bromine / 38 - 45 °C
2: /BRN= 361252/
View Scheme
参考文献
Fischer; Halbig
Justus Liebigs Annalen der Chemie, 1926 , vol. 447, p. 126,137
Justus Liebigs Annalen der Chemie, 1926 , vol. 448, p. 199
反应条件
1: 42 percent / bromine / acetic acid / 0.5 h / 40 - 43 °C
2: 50 percent / aq. HBr / methanol / 7 h / Heating
3: NaOH / ethanol; H2O / 3 h / Heating
View Scheme
参考文献
Byun; Lightner
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1683 - 1692
反应条件
sulfuryl dichloride; bromine; acetic acid
Reagens 4: Acetanhydrid; anschliessend Behandeln mit H2O;
参考文献
Corwin; Straughn
Journal of the American Chemical Society, 1948 , vol. 70, p. 1416,1420
Full Text Show Details
Corwin et al.
Journal of the American Chemical Society, 1942 , vol. 64, p. 1267,1271
反应条件
sulfuryl dichloride; bromine; acetic acid
T=10 - 20°C;
参考文献
Nikitin, Edward B.; Dey, Sanjeev K.; Lightner, David A.
Monatshefte fur Chemie, 2009 , vol. 140, # 1 p. 97 - 110
反应条件
1: 67 percent / sulphuryl chloride / acetic acid / 0.5 h / 50 °C
2: 1.) tetrabutylammonium bromide, 30percent aq. potassium hydroxide / 1.) chloroform, 20 deg C, 1 h, 2.) irradiation, 3 h
3: 89 percent / H2 / 10percent palladium-carbon / acetic acid / 36 h / 735.5 Torr / Ambient temperature
View Scheme
参考文献
Corwin et al.
Journal of the American Chemical Society, 1942 , vol. 64, p. 1267,1271
反应条件
sulfuric acid
T=40°C;
参考文献
Berezin, M. V.; Semeikin, A. S.; V'yugin, A. I.; Krestov, G. A.
Russian Chemical Bulletin, 1993 , vol. 42, # 3 p. 449 - 453
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 3 p. 495 - 499
反应条件
1: bromine; SO2Cl2; acetic acid / Reagens 4: Acetanhydrid; anschliessend Behandeln mit H2O
2: aqueous NaOH
View Scheme
参考文献
Corwin; Straughn
Journal of the American Chemical Society, 1948 , vol. 70, p. 1416,1420
