1-(4-甲基苯基)-2-苯基乙烷-1,2-二酮合成路线 （共 60 条）
反应条件
1: 1.) n-BuLi / 1.) toluene, hexane, 15 min, 2.) toluene, hexane, 3 h 2: 63 percent / KMnO4, aq. MgSO4 / toluene / 70 h / 50 - 60 °C View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 101, # 1-4 p. 281 - 286
反应条件
1: 1.) n-BuLi / 1.) toluene, hexane, 15 min, 2.) toluene, hexane, 3 h 2: 63 percent / KMnO4, aq. MgSO4 / toluene / 70 h / 50 - 60 °C View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 101, # 1-4 p. 281 - 286
反应条件
1: Na(1+)*(SiMe3)2N(1-) / tetrahydrofuran / -60 °C 2: tetrahydrofuran / 1.) -30 deg C, 6 h, 2.) r.t. View Scheme
参考文献
Chemische Berichte, , vol. 119, # 4 p. 1350 - 1360
反应条件
1: Na(1+)*(SiMe3)2N(1-) / tetrahydrofuran / -60 °C 2: tetrahydrofuran / Ambient temperature View Scheme
参考文献
Chemische Berichte, , vol. 119, # 4 p. 1350 - 1360
反应条件
1: di-isopropylamine, BuLi / tetrahydrofuran; hexane / 1.) -78 deg C, 1 h; 2.) room temp. 1 h 2: 61 percent / tetrahydrofuran / 1.) -78 deg C, 2 h; 2.) room temp. 1 h 3: 88 percent / 10M HCl / tetrahydrofuran / 5 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 819 - 824
反应条件
1.1: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 0 °C / |Inert atmosphere 1.2: 4 h / 20 °C / |Inert atmosphere 2.1: hydrogen / methanol / 5 h / 3620.13 Torr / |Inert atmosphere 3.1: pyridinium chlorochromate / dichloromethane / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Tetrahedron Letters, , vol. 53, # 39 p. 5327 - 5330
反应条件
BrClMg P=22800 Torr; 2 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Journal of Organometallic Chemistry, , vol. 356, p. 125 - 132
反应条件
BrClMg P=22800 Torr; 2 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Journal of Organometallic Chemistry, , vol. 356, p. 125 - 132
反应条件
1: sodium acetate; [Pd2(allyl)2(3,6-bis(1-(2-pyridylmethyl)imidazol-2-yliden-3-yl)pyridazine)](PF6)2 / 1-methyl-pyrrolidin-2-one / 5 h / 130 °C / |Schlenk technique; |Inert atmosphere 2: sodium iodide; tert.-butylhydroperoxide; [Ru2Cl(3,6-bis(1-(2-pyridylmethyl)imidazol-2-yliden-3-yl)pyridazine)(CH3CN)4](PF6)3 / acetonitrile; water / 0.17 h / 20 °C View Scheme
参考文献
Organometallics, , vol. 31, # 18 p. 6614 - 6622
反应条件
tellurium (IV) oxide; acetic acid 3 h; Heating;
参考文献
Chemistry Letters, , p. 821 - 822
