3-(2-氧代吡咯烷-1-基) 丙酸甲酯合成路线 （共 8 条）
反应条件
N-benzyl-trimethylammonium hydroxide in 1,4-dioxane 72 h; Ambient temperature;
参考文献
Gramain, Jean-Claude; Remuson, Roland
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2341 - 2346
反应条件
toluene-4-sulfonic acid 20 h; Heating;
参考文献
Takahata; Okajima; Yamazaki
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 12 p. 3632 - 3638
反应条件
1: acetonitrile 2: hydrogen chloride View Scheme
参考文献
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 1,211
反应条件
1: 150 °C 2: hydrogen chloride View Scheme
参考文献
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 1,211
反应条件
lithium aluminium tetrahydride in diethyl ether 11 h; Heating;
参考文献
Gribble; Switzer; Soll
Journal of Organic Chemistry, 1988 , vol. 53, # 14 p. 3164 - 3170
反应条件
sodium hydroxide; water
参考文献
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 1,211
反应条件
1: 80 percent / 5 h / 170 - 180 °C
2: polyphosphate ester / CHCl3 / reflux, 4.5 h then R.T., 8 h
View Scheme
参考文献
Takahata; Okajima; Yamazaki
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 12 p. 3632 - 3638
反应条件
hydrazine hydrate in ethanol
2 h; Heating;
参考文献
Gramain, Jean-Claude; Remuson, Roland
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2341 - 2346
