反应条件
1: 1.) NaH / 1.) DMF, 0 ged C, 15 min, 2.) DMF, a) 0 deg C, 30 min, b) RT, 30 min 2: 100 percent / 89percent formic acid / 0.33 h / Ambient temperature 3: 86 percent / N,N-diisopropylethylamine / CH2Cl2 / 2 h / Ambient temperature 4: 67 percent / tetrahydrofuran / 0.67 h / -40 °C 5: pivalic acid / xylene / 6 h / 135 - 140 °C 6: PPTS / 2-methyl-propan-2-ol / 6 h / 80 °C 7: 98 percent / aq. LiOH / methanol / 12 h View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 75, # 6 p. 641 - 645
