1-甲基-4-哌啶甲酸乙酯合成路线 （共 22 条）
反应条件
hydrogen; palladium on activated charcoal in water; acetic acid T=20°C; P=2999.46 Torr; 3.5 h;
参考文献
SYNTARGA B.V.; GEORG-AUGUST-UNIVERSITAet GOeTTINGEN STIFTUNG OeFFENTLICHEN RECHTS (OHNE BEREICH HUMANMEDIZIN)
Patent: WO2007/89149 A2, 2007 ;
Location in patent: Page/Page column 96 ;
反应条件
hydrogenchloride; sodium hydrogencarbonate in 1,4-dioxane; dichloromethane
参考文献
AstraZeneca AB
Patent: US7235559 B1, 2007 ;
US 7235559 B1
反应条件
potassium carbonate in acetonitrile T=15 - 30°C; 2 h;
参考文献
EP1602362 A1, ;
Page/Page column 60 ;
反应条件
hydrogen; palladium on activated charcoal in ethanol P=2250.2 - 3000.2 Torr; 24 h;
参考文献
McKnight, William E.; Proctor, George R.; Sneddon, Andrew H.; Scopes, David I. C.
Journal of Chemical Research, Miniprint, 1987 , # 3 p. 642 - 679
反应条件
sodium hydroxide; formaldehyd; formic acid in water
反应条件
acetic acid; platinum P=51485.6 Torr; Hydrogenation.Hydrieren der Reaktionsloesung im Gemisch mit wss. Formaldehyd an Palladium/Kohle;
参考文献
Journal of the American Chemical Society, , vol. 74, p. 3831
反应条件
triethylamine in toluene Heating;
参考文献
Cignarella; Villa; Barlocco
Farmaco, 1993 , vol. 48, # 10 p. 1439 - 1445
反应条件
water; platinum T=80°C; P=73550.8 Torr; Hydrogenation;
参考文献
Helvetica Chimica Acta, , vol. 37, p. 1762,1765
反应条件
1: water containing formic acid; potassium formate / 159 °C 2: ethanolic HCl View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 19, p. 949,951
反应条件
T=150°C; im Rohr und Kochen des Reaktionsprodukts mit alkoh. Salzsaeure;
参考文献
Chemische Berichte, , vol. 51, p. 819
Chemische Berichte, , vol. 52, p. 208
