甲基N-[(苄氧基)羰基]-L-缬氨酸酯合成路线 (共 35 条)
参考文献
Miyazawa, Toshifumi; Tanaka, Kayoko; Ensatsu, Eiichi; Yanagihara, Ryoji; Yamada, Takashi
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 1 p. 87 - 93
反应条件
1: (2R,5S)-2-(3-tert-Butoxy-benzyl)-5-isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazine With hydrogenchloride 2: N-(benzyloxycarbonyloxy)-succinimide With sodium carbonate in tetrahydrofuran T=20°C;
参考文献
Bozzoli, Andrea; Kazmierski, Wieslaw; Kennedy, Gordon; Pasquarello, Alessandra; Pecunioso, Angelo
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2759 - 2763
反应条件
1: 153 mg / 2,6-lutidine / CH2Cl2 / 0.25 h 2: 85 percent / n-Bu4NF / tetrahydrofuran / 1 h / 0 °C View Scheme
参考文献
Sakaitani, Masahiro; Ohfune, Yasufumi
Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 870 - 876
反应条件
sodium hydrogencarbonate in water
参考文献
Curcio, Pasquale; Allix, Florent; Pickaert, Guillaume; Jamart-Gregoire, Brigitte
Chemistry - A European Journal, 2011 , vol. 17, # 48 p. 13603 - 13612
反应条件
bromine; sodium hydrogencarbonate in water
参考文献
Chen, Anqi,; Savage, Ian; Thomas, Eric J.; Wilson, Peter D.
Tetrahedron Letters, 1993 , vol. 34, # 42 p. 6769 - 6772
反应条件
1: aqueous NaOH View Scheme
参考文献
Synge
Biochemical Journal, 1948 , vol. 42, p. 99,101
反应条件
1: aqueous NaOH View Scheme
参考文献
Synge
Biochemical Journal, 1948 , vol. 42, p. 99,101
反应条件
in dichloromethane T=23°C; 20 h;
参考文献
Chen, Francis M. F.; Benoiton, N. Leo
Canadian Journal of Chemistry, 1987 , vol. 65, p. 619 - 625
反应条件
tetrahydrofuran anschliessend Behandeln mit Triaethylamin in Aether und Behandeln des Reaktionsgemisches mit Methanol;
参考文献
Miyoshi
Bulletin of the Chemical Society of Japan, 1973 , vol. 46, p. 1489,1490,1494
反应条件
T=-5°C; 504 h; Yield given;
参考文献
Chen, Francis M. F.; Benoiton, N. Leo
Canadian Journal of Chemistry, 1987 , vol. 65, p. 619 - 625