5-甲基异喹啉-1(2H)-酮合成路线 （共 5 条）
反应条件
oxygen; Trimethylene glycol; copper(l) chloride; palladium dichloride in ethylene glycol dimethyl ether
参考文献
Izumi, Taeko; Nishimoto, Yasuhiro; Kohei, Kunihiro; Kasahara, Akira
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 5 p. 1419 - 1424
反应条件
1: 75 percent / tri-o-tolylphosphine, Et3N / Pd(II) acetate / acetonitrile / 24 h / 120 °C / 22800 Torr 2: 84 percent / O2, 1,3-propanediol / PdCl2, CuCl / 1,2-dimethoxy-ethane View Scheme
参考文献
Izumi, Taeko; Nishimoto, Yasuhiro; Kohei, Kunihiro; Kasahara, Akira
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 5 p. 1419 - 1424
反应条件
1: 70 percent / K2CO3 / benzene / 18 h / Ambient temperature 2: H2SO4 / 72 h / 25 °C View Scheme
参考文献
Li; Nair; Edwards; Kisliuk; Gaumont; Dev; Duch; Humphreys; Smith; Ferone
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2746 - 2754
反应条件
1: SOCl2 / benzene 2: 70 percent / K2CO3 / benzene / 18 h / Ambient temperature 3: H2SO4 / 72 h / 25 °C View Scheme
参考文献
Li; Nair; Edwards; Kisliuk; Gaumont; Dev; Duch; Humphreys; Smith; Ferone
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2746 - 2754
反应条件
hydrogen; palladium on activated charcoal in acetic acid T=25°C; P=2585.74 Torr;
参考文献
Showalter; Sercel; Stier; Turner
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 4 p. 961 - 964
