4-(4-甲氧苯基)-1-丁烯-4-醇合成路线 （共 10 条）
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in water T=90 - 100°C; Isomerization; 1.5 h;
参考文献
Wang, Dong; Chen, Dongli; Haberman, John X.; Li, Chao-Jun
Tetrahedron, 1998 , vol. 54, # 20 p. 5129 - 5142
反应条件
palladium diacetate; sodium hydrogencarbonate; lithium chloride in N,N-dimethyl-formamide T=50°C; 0.5 h; Inert atmosphere; regioselective reaction;
参考文献
Crawley, Matthew L.; Phipps, Kristin M.; Goljer, Lgor; Mehlmann, John F.; Lundquist, Joseph T.; Ullrich, John W.; Yang, Cuijian; Mahaney, Paige E.
Organic Letters, 2009 , vol. 11, # 5 p. 1183 - 1185
反应条件
tris(triphenylphosphine)ruthenium(II) chloride; air in water T=90 - 100°C; 1.5 h;
参考文献
Journal of the American Chemical Society, , vol. 117, # 51 p. 12867 - 12868
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in water T=90 - 100°C; Isomerization; 1.5 h;
参考文献
Tetrahedron, , vol. 54, # 20 p. 5129 - 5142
反应条件
trifluorormethanesulfonic acid in acetonitrile T=0 - 20°C; 2 h;
参考文献
Wilsdorf, Michael; Leichnitz, Daniel; Reissig, Hans-Ulrich
Organic Letters, 2013 , vol. 15, # 10 p. 2494 - 2497
反应条件
1: O3 / CH2Cl2; methanol / -78 °C
2: NaBH4 / CH2Cl2; methanol / 0 °C
View Scheme
参考文献
Itoh, Tetsuji; Watanabe, Manabu; Fukuyama, Tohru
Synlett, 2002 , # 8 p. 1323 - 1325
反应条件
1: Zn/Cu
2: PCC
View Scheme
参考文献
Bloodworth, A. J.; Korkodilos, Despoina
Tetrahedron Letters, 1991 , vol. 32, # 47 p. 6953 - 6956
反应条件
tert.-butylhydroperoxide; zirconium tetra-n-propoxide in dichloromethane
T=20°C; 6 h;
参考文献
Krohn, Karsten; Khanbabaee, Karamali; Rieger, Hagen
Chemische Berichte, 1990 , vol. 123, # 6 p. 1357 - 1364
反应条件
p-CO2H-IBX in water; acetonitrile
T=65°C; 12 h;
参考文献
Kommreddy, Amitha; Bowsher, Michael S.; Gunna, Meena R.; Botha, Kirankumar; Vinod, Thottumkara K.
Tetrahedron Letters, 2008 , vol. 49, # 28 p. 4378 - 4382
反应条件
1: 75 percent / pyridinium dichromate / CH2Cl2 / 24 h
2: 73 percent / tetrahydrofuran / 1) -70 deg C, 1 h, 2) 0 deg C, 2 h, 3) reflux, 2 h
3: 60 percent / HOAc / xylene / 7 h / Heating
4: 80 percent / H2 / 10percent Pd-C / ethanol / 0.25 h / 775.7 Torr
5: 35 percent / TosOH / benzene / 2 h / Heating
View Scheme
参考文献
Jayaraman, S.; Raju, N.; Rajagopalan, K.
Steroids, 1982 , vol. 40, # 3 p. 267 - 274
