3-(4-氯苯基)-5-苯基异恶唑合成路线 （共 19 条）
反应条件
triethylamine in diethyl ether
48 h; Ambient temperature;
参考文献
Bandiera, T.; Gruenanger, P.; Albini, F. Marinone
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 6 p. 1423 - 1428
反应条件
Magtrievetrade; in acetonitrile
T=80°C; 2 h;
参考文献
Bhosale, Sandeep; Kurhade, Santosh; Prasad, Uppuleti Viplava; Palle, Venkata P.; Bhuniya, Debnath
Tetrahedron Letters, 2009 , vol. 50, # 27 p. 3948 - 3951
反应条件
1: With TsNHOH; potassium carbonate in methanol; water
T=40°C; 24 h;
2: With potassium carbonate in methanol; water
T=60°C; 10 h; regiospecific reaction;
参考文献
Tang, Shibing; He, Jinmei; Sun, Yongquan; He, Liuer; She, Xuegong
Organic Letters, 2009 , vol. 11, # 17 p. 3982 - 3985
反应条件
sodium hydroxide; hydroxylamine hydrochloride
T=65°C; 5.5 h; Ionic liquid;
参考文献
Valizadeh, Hassan; Amiri, Mohammad; Gholipur, Hamid
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 1 p. 108 - 110
反应条件
1: hydroxylamine hydrochloride / water / 0.5 h / 20 °C / |Green chemistry
2: N-chloro-succinimide / 3 h / |Green chemistry
3: sodium azide / 3 h / |Green chemistry
View Scheme
参考文献
Bharate, Sandip B.; Padala, Anil K.; Dar, Bashir A.; Yadav, Rammohan R.; Singh, Baldev; Vishwakarma, Ram A.
Tetrahedron Letters, 2013 , vol. 54, # 27 p. 3558 - 3561
反应条件
in diethyl ether
T=0 - 10°C;
参考文献
Baranski, Andrzej
Polish Journal of Chemistry, 1986 , vol. 60, # 4-6 p. 419 - 427
反应条件
in various solvent(s)
Heating;
参考文献
Baranski, Andrzej; Cholewka, Elzbieta
Polish Journal of Chemistry, 1989 , vol. 63, # 4-12 p. 483 - 494
反应条件
1: NaH / toluene / 115 - 120 °C
2: aq. KOH / bis-(2-hydroxy-ethyl) ether / 150 °C
View Scheme
参考文献
Renfrow,W.B. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 1 p. 150 - 153
反应条件
triethylamine in N,N-dimethyl-formamide
0.666667 h; Ambient temperature;
参考文献
Gewald, Karl; Hain, Ute
Zeitschrift fuer Chemie (Stuttgart, Germany), 1986 , vol. 26, # 12 p. 434 - 435
反应条件
1: 55 percent / dioxane / 5 h / Ambient temperature
2: 36 percent / aq. KOH / dioxane / 4 h / 101 °C
View Scheme
参考文献
Balasundaram, B.; Perumal, P.T.
Synthetic Communications, 1990 , vol. 20, # 20 p. 3161 - 3166
