4-溴-2,3,5,6-四氯吡啶合成路线 （共 21 条）
反应条件
trichloromonobromomethane; tetrabutylammomium bromide; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide in sodium hydroxide T=50°C;
参考文献
Joshi, Ashutosh V.; Baidossi, Mubeen; Qafisheh, Nida; Chachashvili, Elsa; Sasson, Yoel
Tetrahedron Letters, 2004 , vol. 45, # 26 p. 5061 - 5063
反应条件
1: C2Cl6; nBu4NBr; aq. NaOH / 4 h / 50 °C 2: CBrCl3; nBu4NBr; EDC / aq. NaOH / 50 °C View Scheme
参考文献
Joshi, Ashutosh V.; Baidossi, Mubeen; Qafisheh, Nida; Chachashvili, Elsa; Sasson, Yoel
Tetrahedron Letters, 2004 , vol. 45, # 26 p. 5061 - 5063
反应条件
copper; benzoyl chloride in N,N-dimethyl-formamide T=150°C; 0.5 h;
参考文献
Mack, Arthur G.; Suschitzky, Hans; Wakefield, Basil J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1682 - 1687
反应条件
para-xylene; copper in N,N-dimethyl-formamide T=150°C; 1 h; Further byproducts given;
参考文献
Mack, Arthur G.; Suschitzky, Hans; Wakefield, Basil J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1682 - 1687
反应条件
isopropyl-benzene; copper in N,N-dimethyl-formamide T=150°C; 1 h; Further byproducts given;
参考文献
Mack, Arthur G.; Suschitzky, Hans; Wakefield, Basil J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1682 - 1687
反应条件
para-xylene; copper in N,N-dimethyl-formamide T=150°C; 1 h; the similar reaction without p-xylene; in presence cumene, benzoyl chloride instead p-xylene; other reagent (CuCl); other polychloroiodoarenes; tetrahalohenopyridylcopper intermediate; evidence against free radical or pyridyne intermediates; Product distributionMechanism;
参考文献
Mack, Arthur G.; Suschitzky, Hans; Wakefield, Basil J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1682 - 1687
反应条件
copper; benzoyl chloride in N,N-dimethyl-formamide T=150°C; 0.5 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1682 - 1687
反应条件
para-xylene; copper in N,N-dimethyl-formamide T=150°C; 1 h; Further byproducts given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1682 - 1687
反应条件
isopropyl-benzene; copper in N,N-dimethyl-formamide T=150°C; 1 h; Further byproducts given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1682 - 1687
反应条件
1: 16 percent / copper bronze, cumene / dimethylformamide / 1 h / 150 °C 2: 3 percent Chromat. / copper bronze / dimethylformamide / 20 h / 150 °C View Scheme
参考文献
Mack, Arthur G.; Suschitzky, Hans; Wakefield, Basil J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1682 - 1687
