3-(3-羟基丙氧基)丙-1-醇合成路线 （共 21 条）
反应条件
hydrogen bromide; acetic acid und Erhitzen des Reaktionsprodukts mit Alkalilauge;
参考文献
SHOWA DENKO K.K.
Patent: WO2005/75392 A2, 2005 ;
Location in patent: Page/Page column 64-65 ;
反应条件
und Erhitzen des Reaktionsprodukts mit Alkalilauge;
参考文献
Rojahn
Chemische Berichte, 1921 , vol. 54, p. 3119
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
Reduction; 0.75 h;
参考文献
Buchanan; Driega; Yap
Canadian Journal of Chemistry, 2000 , vol. 78, # 3 p. 316 - 321
反应条件
hydrogen; palladium on activated charcoal in methanol
P=760 Torr; 5 h;
参考文献
Knuf, Erin C.; Jiang, Jian-Kang; Gin, Mary S.
Journal of Organic Chemistry, 2003 , vol. 68, # 23 p. 9166 - 9169
反应条件
1: With trifluorormethanesulfonic acid
T=180°C; Inert atmosphere;
2: With XUS ion exchange resin
T=105°C; Inert atmosphere;
参考文献
E. I. DU PONT DE NEMOURS AND COMPANY
Patent: US2011/224307 A1, 2011 ;
Location in patent: Page/Page column 7 ;
反应条件
1: With hydrogenchloride
2: With sulfuric acid in ethanol
3: With lithium aluminium tetrahydride in tetrahydrofuran
参考文献
ESPERION THERAPEUTICS, INC.
Patent: WO2005/68410 A1, 2005 ;
Location in patent: Page/Page column 232 ;
WO 2005/068410 A1
反应条件
M31 strong acid form cationic exchange resin
12 h; Conversion of starting material;
参考文献
Powell, Joseph Broun; Weider, Paul Richard; Komplin, Glenn Charles
Patent: US2004/87819 A1, 2004 ;
Location in patent: Page 4 ;
反应条件
USY H+ zeolite
T=150°C; 24 h; Conversion of starting material;
参考文献
Brewer, Stephen Edward; Diaz, Zaida; Powell, Joseph Broun; Weider, Paul Richard; Komplin, Glenn Charles; Blackbourn, Robert Lawrence
Patent: US2004/87818 A1, 2004 ;
Location in patent: Page 4 ;
反应条件
(i) Na, (ii) /BRN= 773655/; Multistep reaction;
参考文献
Sieber,G.; Ulbricht,I.
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 20, p. 14 - 19
反应条件
Amberlyst A15 resin
T=100°C; 1 - 5 h; Conversion of starting material;
参考文献
Powell, Joseph Broun; Weider, Paul Richard; Komplin, Glenn Charles
Patent: US2004/87819 A1, 2004 ;
Location in patent: Page 3-4 ;
