3-甲基-2-氧代-哌嗪合成路线 （共 16 条）
反应条件
1: 60 percent / methanol / 24 h / Heating 2: 70 percent / lithium aluminium hydride / tetrahydrofuran / 72 h / Heating View Scheme
参考文献
Charles, Elisabeth S.; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 752 - 756
反应条件
in dichloromethane T=20°C; 16 h;
参考文献
Aebi, Johannes; Binggeli, Alfred; Green, Luke; Hartmann, Guido; Maerki, Hans P.; Mattei, Patrizio; Ricklin, Fabienne
Patent: US2009/23713 A1, 2009 ;
Location in patent: Page/Page column 16 ;
US 20090023713 A1
反应条件
1: 60 percent / methanol / 24 h / Heating 2: 70 percent / lithium aluminium hydride / tetrahydrofuran / 72 h / Heating 3: 59 percent / formic acid / 10 h / Heating 4: 25 percent / benzene / 48 h / Heating View Scheme
参考文献
Charles, Elisabeth S.; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 752 - 756
反应条件
1: 60 percent / methanol / 24 h / Heating 2: 70 percent / lithium aluminium hydride / tetrahydrofuran / 72 h / Heating 3: 67 percent / triethylamine / benzene / Heating 4: 70 percent / hydrogen / 10percent Pd-C / acetic acid / 12 h / 1838.8 Torr 5: 63 percent / triethylamine / acetone / Ambient temperature View Scheme
参考文献
Charles, Elisabeth S.; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 752 - 756
反应条件
1: 60 percent / methanol / 24 h / Heating
2: 70 percent / lithium aluminium hydride / tetrahydrofuran / 72 h / Heating
3: 60 percent / triethylamine / benzene / Heating
4: 68 percent / hydrogen / 10percent Pd-C / acetic acid / 1838.8 Torr
5: 68 percent / triethylamine / acetone / 48 h / Ambient temperature
View Scheme
参考文献
Charles, Elisabeth S.; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 752 - 756
反应条件
1: 60 percent / methanol / 24 h / Heating
2: 70 percent / lithium aluminium hydride / tetrahydrofuran / 72 h / Heating
3: 60 percent / triethylamine / benzene / Heating
4: 68 percent / hydrogen / 10percent Pd-C / acetic acid / 1838.8 Torr
View Scheme
参考文献
Charles, Elisabeth S.; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 752 - 756
