2-肼基-4,6-二甲基嘧啶合成路线 （共 13 条）
反应条件
hydrazine hydrate in ethanol T=20°C; 2 h;
参考文献
PROTEOSTASIS THERAPEUTICS, INC.; TAIT, Bradley; POWELL, Noel, A.; CULLEN, Matthew
Patent: WO2012/154880 A1, 2012 ;
Location in patent: Page/Page column 60 ;
反应条件
hydrazine hydrate in ethanol 7 h; Heating;
参考文献
Vio; Mamolo
Farmaco, Edizione Scientifica, 1983 , vol. 38, # 4 p. 255 - 264
反应条件
hydrazine hydrate in ethanol 6 h; Heating;
参考文献
Danagulyan, G. G.; Balasanyan, N. G.; Terent'ev, P. B.; Zalinyan, M. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 12 p. 1369 - 1373
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , # 12 p. 1644 - 1648
反应条件
1: 80 percent / HCl / ethanol / 2 h / Heating 2: 60 percent / aq. KOH 3: 60 percent / hydrazine hydrate / ethanol / 6 h / Heating View Scheme
参考文献
Bollettino chimico farmaceutico, , vol. 143, # 7 p. 275 - 279
反应条件
1: 60 percent / aq. KOH 2: 60 percent / hydrazine hydrate / ethanol / 6 h / Heating View Scheme
参考文献
Bollettino chimico farmaceutico, , vol. 143, # 7 p. 275 - 279
参考文献
Yakugaku Zasshi, , vol. 79, p. 1487,1491
Chem.Abstr., , p. 11039
参考文献
Farmaco, Edizione Scientifica, , vol. 11, p. 389,393
反应条件
potassium hydroxide in ethanol 5 h; Heating;
参考文献
Al-Ashmawy; Abd El-Samii; El Feky; Osman
Bollettino Chimico Farmaceutico, 1998 , vol. 137, # 4 p. 110 - 114
参考文献
Bower; Doyle
Journal of the Chemical Society, 1957 , p. 727,732
参考文献
Boarland et al.
Journal of the Chemical Society, 1952 , p. 4691,4694
