1: lithium diisopropyl amide / tetrahydrofuran / 4 h / -78 °C 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / Reflux 3: trichlorophosphate / 1 h / 20 °C 4: hydroxylamine hydrochloride; sodium acetate / 1,4-dioxane / 24 h / Reflux 5: 10 palladium on activated charcoal / 1,2-dichloro-benzene / Reflux View Scheme

1: trichlorophosphate / 1 h / 20 °C 2: hydroxylamine hydrochloride; sodium acetate / 1,4-dioxane / 24 h / Reflux 3: 10 palladium on activated charcoal / 1,2-dichloro-benzene / Reflux View Scheme

1: hydroxylamine hydrochloride; sodium acetate / 1,4-dioxane / 24 h / Reflux 2: 10 palladium on activated charcoal / 1,2-dichloro-benzene / Reflux View Scheme

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / Reflux 2: trichlorophosphate / 1 h / 20 °C 3: hydroxylamine hydrochloride; sodium acetate / 1,4-dioxane / 24 h / Reflux 4: 10 palladium on activated charcoal / 1,2-dichloro-benzene / Reflux View Scheme

1.1: trifluoroacetic acid / dichloromethane / 12 h / 20 °C / Inert atmosphere 2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 2.2: 12 h / 20 °C / Inert atmosphere; Cooling with ice 3.1: lithium hydroxide hydrate / tetrahydrofuran; water / 12 h / 60 °C 3.2: 20 °C 4.1: diphenyl phosphoryl azide; triethylamine / toluene / 0.17 h / 100 °C / Inert atmosphere; Microwave irradiation 5.1: pyridine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 6.1: triethylsilane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate / N,N-dimethyl-formamide / 1 h / 60 °C / Inert atmosphere 7.1: methanol; trifluorormethanesulfonic acid; trimethyl orthoformate / nitromethane / 1 h / 100 °C / Inert atmosphere; Cooling with ice View Scheme

1.1: lithium hydroxide hydrate / tetrahydrofuran; water / 12 h / 60 °C 1.2: 20 °C 2.1: diphenyl phosphoryl azide; triethylamine / toluene / 0.17 h / 100 °C / Inert atmosphere; Microwave irradiation 3.1: pyridine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 4.1: triethylsilane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate / N,N-dimethyl-formamide / 1 h / 60 °C / Inert atmosphere 5.1: methanol; trifluorormethanesulfonic acid; trimethyl orthoformate / nitromethane / 1 h / 100 °C / Inert atmosphere; Cooling with ice View Scheme

1: diphenyl phosphoryl azide; triethylamine / toluene / 0.17 h / 100 °C / Inert atmosphere; Microwave irradiation 2: pyridine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 3: triethylsilane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate / N,N-dimethyl-formamide / 1 h / 60 °C / Inert atmosphere 4: methanol; trifluorormethanesulfonic acid; trimethyl orthoformate / nitromethane / 1 h / 100 °C / Inert atmosphere; Cooling with ice View Scheme

1: pyridine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 2: triethylsilane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate / N,N-dimethyl-formamide / 1 h / 60 °C / Inert atmosphere 3: methanol; trifluorormethanesulfonic acid; trimethyl orthoformate / nitromethane / 1 h / 100 °C / Inert atmosphere; Cooling with ice View Scheme

1: triethylsilane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate / N,N-dimethyl-formamide / 1 h / 60 °C / Inert atmosphere 2: methanol; trifluorormethanesulfonic acid; trimethyl orthoformate / nitromethane / 1 h / 100 °C / Inert atmosphere; Cooling with ice View Scheme

1.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethylene glycol dimethyl ether; water / 12 h / Inert atmosphere; Reflux 2.1: trifluoroacetic acid / dichloromethane / 12 h / 20 °C / Inert atmosphere 3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 3.2: 12 h / 20 °C / Inert atmosphere; Cooling with ice 4.1: lithium hydroxide hydrate / tetrahydrofuran; water / 12 h / 60 °C 4.2: 20 °C 5.1: diphenyl phosphoryl azide; triethylamine / toluene / 0.17 h / 100 °C / Inert atmosphere; Microwave irradiation 6.1: pyridine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice 7.1: triethylsilane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate / N,N-dimethyl-formamide / 1 h / 60 °C / Inert atmosphere 8.1: methanol; trifluorormethanesulfonic acid; trimethyl orthoformate / nitromethane / 1 h / 100 °C / Inert atmosphere; Cooling with ice View Scheme