2-氨基-5-甲氧基苯甲腈合成路线 （共 14 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol; ethyl acetate T=20°C; P=1292.9 Torr; 0.333333 h;
参考文献
SCHERING CORPORATION
Patent: WO2009/5646 A2, 2009 ;
Location in patent: Page/Page column 186 ;
WO 2009/005646 A2
反应条件
sodium carbonate in N,N-dimethyl-formamide T=130°C; 2 h;
参考文献
Nakhai, Azadeh; Stensland, Birgitta; Svensson, Per H.; Bergman, Jan
European Journal of Organic Chemistry, 2010 , # 34 p. 6588 - 6599
反应条件
in tetrahydrofuran T=20°C; 1 h;
参考文献
European Journal of Organic Chemistry, , # 34 p. 6588 - 6599
反应条件
1: 88 percent / NH2OH*HCl; MgSO4; p-TsOH*H2O / toluene / 15 h / Heating 2: 56 percent / SnCl2*H2O / methanol / 3 h / 70 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 10, # 10 p. 2487 - 2506
反应条件
1: 96 percent / Cs2CO3 / dimethylformamide / 15 h / 20 °C 2: 88 percent / NH2OH*HCl; MgSO4; p-TsOH*H2O / toluene / 15 h / Heating 3: 56 percent / SnCl2*H2O / methanol / 3 h / 70 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 10, # 10 p. 2487 - 2506
反应条件
1: pyridine; hydroxylamine hydrochloride 2: PCl5 3: aqueous NaOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 80, p. 126,135
反应条件
1: water; sulfuric acid 2: pyridine; hydroxylamine hydrochloride 3: PCl5 4: aqueous NaOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 80, p. 126,135
参考文献
Journal of the American Chemical Society, , vol. 80, p. 126,135
反应条件
1: triethylamine; trifluoroacetic anhydride / dichloromethane / 1 h / 20 °C 2: water; sodium dithionite / ethanol / 1 h / Reflux View Scheme
参考文献
WO2011/112731 A2, ;
WO 2011/112731 A2
反应条件
10 h; Inert atmosphereReflux;
参考文献
Koreeda, Tetsuro; Kochi, Takuya; Kakiuchi, Fumitoshi
Organometallics, 2013 , vol. 32, # 2 p. 682 - 690
