4-羟基-3-甲氧基苯乙醇合成路线 （共 16 条）
反应条件
1: With ozone in ethanol T=-55°C; 2: With sodium tetrahydroborate in ethyl acetate T=20°C;
参考文献
Université de Bordeaux I; Centre National de la Recherche Scientifique (C.N.R.S); Societe Civile Immobiliere Girondina; The designation of the inventor has not yet been filed
Patent: EP2620424 A1, 2013 ;
Location in patent: Page/Page column 0060-0061 ;
反应条件
hydrogen; palladium on activated charcoal in methanol P=750.06 Torr; 1 h;
参考文献
Schweitzer, Stefan; Voss, Gundula; Gerlach, Hans
Liebigs Annalen der Chemie, 1994 , # 2 p. 189 - 192
反应条件
methanol; sodium tetrahydroborate in dichloromethane T=-78 - 20°C; 2 h; Inert atmosphere;
参考文献
WO2012/3625 A1, ;
Page/Page column 8-9 ;
反应条件
copper(I) bromide in N,N-dimethyl-formamide T=120°C; 1 h;
参考文献
Bovicelli, Paolo; Antonioletti, Roberto; Mancini, Silvia; Causio, Stefano; Borioni, Giorgio; Ammendola, Sergio; Barontini, Maurizio
Synthetic Communications, 2007 , vol. 37, # 23 p. 4245 - 4252
反应条件
methanol; trimethylsilyl bromide T=20°C; 5 h; chemoselective reaction;
参考文献
Shah, Syed Tasadaque A.; Guiry, Patrick J.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 12 p. 2168 - 2172
反应条件
1: 1.) Mg, 1,2-dibromoethane, 2.) 1,5-cyclooctadiene copper(I) chloride / 1.) THF, reflux, 5 h, 2.) THF, 0 deg C - 14 deg C, 16 h 2: 91 percent / H2 / 5percent Pd/C / methanol / 1 h / 750.06 Torr View Scheme
参考文献
Liebigs Annalen der Chemie, , # 2 p. 189 - 192
反应条件
erbium trifluoromethanesulfonate in methanol T=100°C; 0.75 h; Microwave irradiation;
参考文献
Synthesis, , # 1 p. 73 - 78
反应条件
acetyl chloride 0.5 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 10 p. 3880 - 3885
反应条件
acetyl chloride 0.5 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 10 p. 3880 - 3885
反应条件
in methanol 0.5 h; Heating; Title compound not separated from byproducts;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 8 p. 3009 - 3014
