(4-甲基苄基)三苯基溴化膦合成路线 （共 21 条）
反应条件
sodium hydroxide; nitrogen(II) oxide in dichloromethane T=20°C; 5 h;
参考文献
Tetrahedron Letters, , vol. 46, # 7 p. 1095 - 1097
反应条件
1.1: n-butyllithium / tetrahydrofuran / 12 h / -78 - 20 °C / Inert atmosphere
1.2: 12 h / Inert atmosphere
2.1: iodine; methyloxirane / cyclohexane / Irradiation; Inert atmosphere
3.1: 1100 °C / 0.08 Torr / Pyrolysis
4.1: 1100 °C / 0.08 Torr / Pyrolysis
View Scheme
参考文献
Amsharov, Konstantin Yu.; Kabdulov, Mikhail A.; Jansen, Martin
European Journal of Organic Chemistry, 2009 , # 36 p. 6328 - 6335
反应条件
1.1: n-butyllithium / tetrahydrofuran / 12 h / -78 - 20 °C / Inert atmosphere
1.2: 12 h / Inert atmosphere
2.1: iodine; methyloxirane / cyclohexane / Irradiation; Inert atmosphere
View Scheme
参考文献
Amsharov, Konstantin Yu.; Kabdulov, Mikhail A.; Jansen, Martin
European Journal of Organic Chemistry, 2009 , # 36 p. 6328 - 6335
反应条件
1: 90 percent / lithium diisopropylamide / tetrahydrofuran / 1 h
2: 59 percent / 280 °C / 10 Torr
View Scheme
参考文献
Kobayashi, Yoshiro; Yamashita, Toshinori; Takahashi, Katsuhiro; Kuroda, Hisashi; Kumadaki, Itsumaro
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 11 p. 4402 - 4409
反应条件
1.1: 44 percent / NaOEt / ethanol
2.1: 97 percent / Zn; NH4Cl / acetone; H2O / Heating
3.1: NaOAc / ethanol / Heating
3.2: 94 percent / H2O / Alkaline hydrolysis
View Scheme
参考文献
Butkovic, Kristina; Marinic, Zeljko; Sindler-Kulyk, Marija
Magnetic Resonance in Chemistry, 2004 , vol. 42, # 12 p. 1053 - 1055
反应条件
2: 1.) BH3 2.) acetic acid / 2.) reflux
3: 1.) Li 2.) CO2 / 1.) ether
4: LiAlH4
View Scheme
参考文献
Camaioni, Donald M.; Franz, James A.
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1607 - 1613
反应条件
2: 1.) BH3 2.) acetic acid / 2.) reflux
View Scheme
参考文献
Camaioni, Donald M.; Franz, James A.
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1607 - 1613
反应条件
2: 1.) BH3 2.) acetic acid / 2.) reflux
3: 1.) Li 2.) CO2 / 1.) ether
View Scheme
参考文献
Camaioni, Donald M.; Franz, James A.
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1607 - 1613
反应条件
(i) PhLi, (ii) /BRN= 2045535/; Multistep reaction;
参考文献
Keaveney,W.P.; Hennessy,D.J.
Journal of Organic Chemistry, 1962 , vol. 27, p. 1057 - 1058
反应条件
potassium tert-butylate in toluene
T=21°C; 24 h;
参考文献
Mulzer, Johann; Huisgen, Rolf; Arion, Vladimir; Sustmann, Reiner
Helvetica Chimica Acta, 2011 , vol. 94, # 8 p. 1359 - 1388
