5-(4-硝基苯基)-1,3,4-恶二唑-2(3H)-硫酮合成路线 （共 10 条）
反应条件
pyridine 4 h; Reflux;
参考文献
Centore, Roberto; Fusco, Sandra; Peluso, Andrea; Capobianco, Amedeo; Stolte, Matthias; Archetti, Graziano; Kuball, Hans-Georg
European Journal of Organic Chemistry, 2009 , # 21 p. 3535 - 3543
反应条件
1: With potassium hydroxide in ethanol; water Reflux; 2: With hydrogenchloride in water pH=2 - 3;
参考文献
Hasan, Aurangzeb; Gapil, Shelly; Khan, Izzat
Asian Journal of Chemistry, 2011 , vol. 23, # 5 p. 2007 - 2010
反应条件
1: hydrazine hydrate / ethanol / 8 h / Reflux 2: potassium hydroxide / ethanol; water / Reflux View Scheme
参考文献
Dash, Sasmita; Kumar, B. Ashok; Singh, Jagadish; Maiti; Maity
Medicinal Chemistry Research, 2011 , vol. 20, # 8 p. 1206 - 1213
反应条件
1: sulfuric acid / 4 h / Reflux 2: hydrazine hydrate / ethanol / 8 h / Reflux 3: potassium hydroxide / ethanol; water / Reflux View Scheme
参考文献
Dash, Sasmita; Kumar, B. Ashok; Singh, Jagadish; Maiti; Maity
Medicinal Chemistry Research, 2011 , vol. 20, # 8 p. 1206 - 1213
反应条件
1: hydrazine hydrate / methanol / 6 h / Heating 2: KOH / ethanol / 8 h / Heating View Scheme
参考文献
Gul, Samreen; Ur-Rehman, Aziz; Abbasi, Muhammad Athar; Nafeesa, Khadija; Malik, Abdul; Ashraf, Muhammad; Ismail, Tayaba; Ahmad, Irshad
Asian Journal of Chemistry, 2013 , vol. 25, # 11 p. 6231 - 6236
反应条件
1: KOH 2: Heating View Scheme
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
反应条件
in N,N-dimethyl-formamide 0.0666667 h; Microwave irradiation; TemperatureTime;
参考文献
Mahesh Kumar; Dubey
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 11 p. 1619 - 1622
反应条件
1: triethylamine / dichloromethane / 0 °C 2: hydrazine hydrate / methanol / 5 h / |Reflux 3: potassium hydroxide / methanol / 20 °C / |Reflux 4: hydrogenchloride / water / 0 - 5 °C View Scheme
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
反应条件
Microwave irradiation;
参考文献
Mahesh Kumar; Dubey
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 11 p. 1619 - 1622
反应条件
in various solvent(s)
T=150 - 160°C; 5 h;
参考文献
Chau, Nguyen; Saegusa, Yasuo; Iwakura, Yoshio
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 541 - 544
