5-氯-2-苯-1H-吲哚合成路线 （共 37 条）
反应条件
zinc dibromide in toluene T=130°C; 24 h;
参考文献
Perea-Buceta, Jesus E.; Wirtanen, Tom; Laukkanen, Otto-Ville; Maekelae, Mikko K.; Nieger, Martin; Melchionna, Michele; Huittinen, Nina; Lopez-Sanchez, Jose A.; Helaja, Juho
Angewandte Chemie - International Edition, 2013 , vol. 52, # 45 p. 11835 - 11839
Angew. Chem., 2013 , vol. 125, # 45 p. 12051 - 12055,5
反应条件
1,10-phenanthroline; carbon monoxide; palladium diacetate in N,N-dimethyl-formamide T=80°C; P=775.722 Torr; 16 h;
参考文献
Davies, Ian W.; Smitrovich, Jacqueline H.; Sidler, Rick; Qu, Chuanxing; Gresham, Venita; Bazaral, Charles
Tetrahedron, 2005 , vol. 61, # 26 p. 6425 - 6437
反应条件
oxygen; acetic acid; palladium diacetate T=20°C; P=760.051 Torr; 20 h;
参考文献
Yang, Shang-Dong; Sun, Chang-Liang; Fang, Zhao; Li, Bi-Jie; Li, Yi-Zhou; Shi, Zhang-Jie
Angewandte Chemie - International Edition, 2008 , vol. 47, # 8 p. 1473 - 1476
反应条件
n-butyllithium in tetrahydrofuran 15 h; -20 deg C to room temperature;
参考文献
Houlihan, William J.; Parrino, Vincent A.; Uike, Yasuyuki
Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4511 - 4515
反应条件
sodium t-butanolate; Pd PEPPSI-IPr in toluene T=215°C; P=3878.71 Torr; microwave irradiation;
参考文献
Shore, Gjergji; Morin, Sylvie; Mallik, Debasis; Organ, Michael G.
Chemistry - A European Journal, 2008 , vol. 14, # 4 p. 1351 - 1356
反应条件
cobalt/rhodium in tetrahydrofuran T=90°C; P=15201 Torr; 5 h;
参考文献
Park, Ji Hoon; Kim, Eunha; Chung, Young Keun
Organic Letters, 2008 , vol. 10, # 21 p. 4718 - 4721
反应条件
1: in neat (no solvent) T=20°C; Bischler-Moehlau Indole Synthesis; 3 h; Green chemistry; 2: With N,N-dimethyl-formamide in neat (no solvent) Bischler-Moehlau Indole Synthesis; 0.0166667 h; Microwave irradiationGreen chemistry;
参考文献
European Journal of Medicinal Chemistry, , vol. 80, p. 509 - 522
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in N,N-dimethyl acetamide T=20°C; Sonogashira Cross-Coupling; 1 h; 2: With sodium hydroxide in N,N-dimethyl acetamide T=140°C;
参考文献
Yu, Xufen; Park, Eun-Jung; Kondratyuk, Tamara P.; Pezzuto, John M.; Sun, Dianqing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 44 p. 8835 - 8847
反应条件
copper(l) iodide; ethanolamine; triphenylphosphine; palladium on activated charcoal in water T=80°C; 4 h;
参考文献
Pal, Manojit; Subramanian, Venkataraman; Batchu, Venkateswara Rao; Dager, Indu
Synlett, 2004 , # 11 p. 1965 - 1969
反应条件
sulfuric acid; silver(I) acetate; palladium dichloride in N,N-dimethyl-formamide; acetonitrile T=100°C; 0.666667 h; Sealed tubeMicrowave irradiation; regioselective reaction;
参考文献
Miao, Tao; Li, Pinhua; Wang, Guan-Wu; Wang, Lei
Chemistry - An Asian Journal, 2013 , vol. 8, # 12 p. 3185 - 3190
