2-疏基-6-苯基-5H-吡咯并[3,2-d]嘧啶-4-醇合成路线 （共 3 条）
反应条件
1: in benzene T=90°C; 1 h; 2: With potassium hydroxide T=100°C; 15 h; Further stages.;
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
反应条件
1.1: 57 percent / Et3N / CH2Cl2 / 23 h / 0 - 22 °C 2.1: NaOEt / ethanol / 2 h / 20 °C 3.1: benzene / 1 h / 90 °C 3.2: 1.2 g / aq. KOH / 15 h / 100 °C View Scheme
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
反应条件
1.1: NaOEt / ethanol / 2 h / 20 °C 2.1: benzene / 1 h / 90 °C 2.2: 1.2 g / aq. KOH / 15 h / 100 °C View Scheme
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
