1-(1-甲基-2-吡咯基)-2-氯乙酮合成路线 (共 6 条)
反应条件
zinc oxide in neat (no solvent) T=20°C; Friedel-Crafts Acylation; 0.05 h; Green chemistry; regioselective reaction;
参考文献
Zhang, Shuguang; Feng, Chengliang; Cai, Jin; Chen, Junqing; Hu, Huayou; Ji, Min
Journal of Chemical Research, 2013 , vol. 37, # 8 p. 480 - 482
反应条件
N,N,N-trimethylbenzenemethanaminium dichloroiodate in tetrahydrofuran Ambient temperature;
参考文献
Croce, Piero Dalla; Ferraccioli, Rafaella; Ritieni, Alberto
Synthesis, 1990 , # 3 p. 212 - 213
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran; diethyl ether T=-78°C; 0.25 h; 2: With hydrogenchloride; ethanol in 1,2-dichloro-ethane T=20°C; Further stages.;
参考文献
Yoshimatsu, Mitsuhiro; Sakai, Miho; Moriura, Eri
European Journal of Organic Chemistry, 2007 , # 3 p. 498 - 507
反应条件
trichlorophosphate 1.) room temp., 6 h, 2.) 1,2-dichloroethane, room temp., 16 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Synthesis, , # 10 p. 783 - 784
反应条件
trichlorophosphate 1.) room temp., 6 h, 2.) 1,2-dichloroethane, room temp., 16 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Synthesis, , # 10 p. 783 - 784
反应条件
aluminium trichloride in 1,2-dichloro-ethane T=25°C; 16 h;
参考文献
Carson, John R.; Carmosin, Richard J.; Pitis, Philip M.; Vaught, Jeffry L.; Almond, Harold R.; Stables, James P.; Wolf, Harold H.; Swinyard, Ewart A.; White, H. Steve
Journal of Medicinal Chemistry, 1997 , vol. 40, # 11 p. 1578 - 1584