6-氯咪唑并[2,1-b][1,3]噻唑-5-甲醛合成路线 （共 3 条）
反应条件
sodium hypochlorite; sodium dihydrogenphosphate in water; tert-butyl alcohol T=20°C; 8 h;
参考文献
Actelion Phamaceuticals Ltd.
Patent: US2010/16401 A1, 2010 ;
Location in patent: Page/Page column 47 ;
反应条件
in ethanol; water 0.166667 h; Heating;
参考文献
Andreani; Rambaldi; Mascellani; Rugarli
European Journal of Medicinal Chemistry, 1987 , vol. 22, # 1 p. 19 - 22
反应条件
sodium tetrahydroborate in methanol 1.) 3 h 15 min, r.t; 2.) 1 h, reflux;
参考文献
Andreani, A.; Bonazzi, D.; Rambaldi, M.
Farmaco, Edizione Scientifica, 1980 , vol. 35, # 11 p. 896 - 901
