3-(n-苄胺)丙酸甲酯合成路线 （共 24 条）
参考文献
Lima, Paulo G.; Sequeira, Lucia C.; Costa, Paulo R.R.
Tetrahedron Letters, 2001 , vol. 42, # 21 p. 3525 - 3527
反应条件
copper in methanol T=20°C; Aza-Michael Addition; 0.3 h;
参考文献
Synlett, , # 14 p. 2246 - 2250
反应条件
methanol; sodium tetrahydroborate T=-40 - -20°C; 2 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; ORWAT, Michael J.; PINTO, Donald J.P.; SMITH II, Leon M.; SRIVASTAVA, Shefali; CORTE, James R.
Patent: WO2013/55984 A1, 2013 ;
Location in patent: Paragraph 00377 ;
反应条件
in tetrahydrofuran T=40°C; 1 h;
参考文献
Gill; Freeman; Irwin; Wilson
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 11 p. 847 - 859
反应条件
Candida antarctica lipase on acrylic resin/Novozyme 435 in hexane T=60°C; Michael Addition; 4 h; Sealed tubeEnzymatic reaction; Reagent/catalyst;
参考文献
Journal of Organic Chemistry, , vol. 78, # 8 p. 3802 - 3813
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=25°C; Michael Addition; 2 h; Inert atmosphere;
参考文献
Green Chemistry, , vol. 15, # 6 p. 1550 - 1557
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=25°C; Michael Addition; 2 h; Inert atmosphere;
参考文献
Green Chemistry, , vol. 15, # 6 p. 1550 - 1557
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=25°C; Michael Addition; 24 h; Inert atmosphere;
参考文献
Green Chemistry, , vol. 15, # 6 p. 1550 - 1557
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=25°C; Michael Addition; 2 h; Inert atmosphere;
参考文献
Green Chemistry, , vol. 15, # 6 p. 1550 - 1557
反应条件
1: triethylamine / dichloromethane / 18 h / 0 °C / |Molecular sieve 2: methanol; sodium tetrahydroborate / 2 h / -40 - -20 °C View Scheme
