3-(哌啶-1-基)丙酸甲酯合成路线 （共 18 条）
反应条件
potassium carbonate; potassium iodide in acetone
4 h; Heating;
参考文献
Meier; Apelt; Reichert; Grassmann; Ligneau; Elz; Leurquin; Ganellin; Schwartz; Schunack; Stark
European Journal of Pharmaceutical Sciences, 2001 , vol. 13, # 3 p. 249 - 259
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
T=25°C; Michael Addition; 2 h; Inert atmosphere;
参考文献
Peeters, Annelies; Ameloot, Rob; De Vos, Dirk E.
Green Chemistry, 2013 , vol. 15, # 6 p. 1550 - 1557
参考文献
Walther et al.
Chemische Berichte, 1956 , vol. 89, p. 60,65
反应条件
benzoic acid in acetone
参考文献
Stamicarbon, B.V.
Patent: US4267362 A1, 1981 ;
反应条件
hydrogen fluoride
T=7 - 8°C; 8.93333 h; electrochemical fluorination; Further byproducts given;
参考文献
Abe, Takashi; Hayashi, Eiji; Fukaya, Haruhiko; Hayakawa, Yoshio; Baba, Hajime; et al.
Journal of Fluorine Chemistry, 1992 , vol. 57, p. 101 - 111
反应条件
hydrogen fluoride
T=7 - 8°C; 8.93333 h; electrochemical fluorination; Yield given. Further byproducts given. Title compound not separated from byproducts;
参考文献
Abe, Takashi; Hayashi, Eiji; Fukaya, Haruhiko; Hayakawa, Yoshio; Baba, Hajime; et al.
Journal of Fluorine Chemistry, 1992 , vol. 57, p. 101 - 111
反应条件
hydrogen fluoride
T=7 - 8°C; 8.93333 h; electrochemical fluorination; Yield given. Further byproducts given. Title compound not separated from byproducts;
参考文献
Abe, Takashi; Hayashi, Eiji; Fukaya, Haruhiko; Hayakawa, Yoshio; Baba, Hajime; et al.
Journal of Fluorine Chemistry, 1992 , vol. 57, p. 101 - 111
反应条件
hydrogen fluoride
T=7 - 8°C; 8.93333 h; electrochemical fluorination; Yield given. Further byproducts given. Title compound not separated from byproducts;
参考文献
Abe, Takashi; Hayashi, Eiji; Fukaya, Haruhiko; Hayakawa, Yoshio; Baba, Hajime; et al.
Journal of Fluorine Chemistry, 1992 , vol. 57, p. 101 - 111
