咪唑并[1,2-a]喹喔啉合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in methanol P=760 Torr;
参考文献
Parra, Stephanie; Laurent, Florence; Subra, Guy; Deleuze-Masquefa, Carine; Benezech, Veronique; Fabreguettes, Jean-Roch; Vidal, Jean-Pierre; Pocock, Tristan; Elliott, Keith; Small, Roger; Escale, Roger; Michel, Alain; Chapat, Jean-Pierre; Bonnet, Pierre-Antoine
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 3 p. 255 - 264
反应条件
potassium phosphate; copper(l) iodide; (-)-sparteine in 1-methyl-pyrrolidin-2-one T=130°C; 24 h;
参考文献
Reeves, Jonathan T.; Fandrick, Daniel R.; Tan, Zhulin; Song, Jinhua J.; Lee, Heewon; Yee, Nathan K.; Senanayake, Chris H.
Journal of Organic Chemistry, 2010 , vol. 75, # 3 p. 992 - 994
反应条件
1.1: HBr / H2O / 1 h / Heating 1.2: 1,2-dimethoxy-ethane; diethyl ether / 48 h / 20 °C 1.3: 49 percent / ethanol / 2 h / Heating 2.1: 98 percent / H2 / 10 percent Pd/C / methanol / 760 Torr View Scheme
参考文献
Parra, Stephanie; Laurent, Florence; Subra, Guy; Deleuze-Masquefa, Carine; Benezech, Veronique; Fabreguettes, Jean-Roch; Vidal, Jean-Pierre; Pocock, Tristan; Elliott, Keith; Small, Roger; Escale, Roger; Michel, Alain; Chapat, Jean-Pierre; Bonnet, Pierre-Antoine
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 3 p. 255 - 264
反应条件
1.1: 90 percent / NH3 / dimethylformamide / 1 h / 0 °C 2.1: HBr / H2O / 1 h / Heating 2.2: 1,2-dimethoxy-ethane; diethyl ether / 48 h / 20 °C 2.3: 49 percent / ethanol / 2 h / Heating 3.1: 98 percent / H2 / 10 percent Pd/C / methanol / 760 Torr View Scheme
参考文献
Parra, Stephanie; Laurent, Florence; Subra, Guy; Deleuze-Masquefa, Carine; Benezech, Veronique; Fabreguettes, Jean-Roch; Vidal, Jean-Pierre; Pocock, Tristan; Elliott, Keith; Small, Roger; Escale, Roger; Michel, Alain; Chapat, Jean-Pierre; Bonnet, Pierre-Antoine
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 3 p. 255 - 264
