molecular sieve in nitrobenzene; toluene T=98 - 100°C; 36 h;

1: 60 percent / K2CO3 / dimethylformamide / 4.5 h / Heating 2: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 3: 1.171 g / AcOH / 12 h / 55 °C 4: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 5: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme

1: 60 percent / K2CO3 / dimethylformamide / 4.5 h / Heating 2: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 3: 1.171 g / AcOH / 12 h / 55 °C 4: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 5: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme

1: HCl gas, molecular sieves 4A / diethyl ether / -20 °C 2: 1.171 g / AcOH / 12 h / 55 °C 3: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 4: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme

1: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 2: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme

1: pyridine / CH2Cl2 / 0.5 h / -20 °C 2: HCl gas, molecular sieves 4A / diethyl ether / -20 °C 3: 1.171 g / AcOH / 12 h / 55 °C 4: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 5: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme

1: 1.171 g / AcOH / 12 h / 55 °C 2: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 3: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme

1: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 2: 1.171 g / AcOH / 12 h / 55 °C 3: H2 / 10percent Pd/C / methanol / 1.25 h / Ambient temperature 4: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme

1: 2.1 g / K2CO3 / acetone / 30 h / Ambient temperature 2: 80 percent / mol. sieves / nitrobenzene; toluene / 36 h / 98 - 100 °C View Scheme