吡咯并[1,2-a]喹喔啉合成路线 （共 9 条）
反应条件
potassium phosphate; copper(l) iodide; (-)-sparteine in 1-methyl-pyrrolidin-2-one T=130°C; 24 h;
参考文献
Reeves, Jonathan T.; Fandrick, Daniel R.; Tan, Zhulin; Song, Jinhua J.; Lee, Heewon; Yee, Nathan K.; Senanayake, Chris H.
Journal of Organic Chemistry, 2010 , vol. 75, # 3 p. 992 - 994
反应条件
boron trifluoride diethyl etherate in dichloromethane T=0°C; 1 h;
参考文献
Kobayashi; Irisawa; Matoba; Matsumoto; Yoneda; Morikawa; Konishi
Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 6 p. 1109 - 1114
反应条件
sodium hydride in tetrahydrofuran T=80°C; 1 h;
参考文献
Mishra, Amita; Batra, Sanjay
European Journal of Organic Chemistry, 2010 , # 25 p. 4832 - 4840
反应条件
pyridine; formaldehyd in ethanol 12 h; Heating;
参考文献
Korakas, Demetrios; Kimbaris, Athanasios; Varvounis, George
Tetrahedron, 1996 , vol. 52, # 32 p. 10751 - 10760
反应条件
hydrogenchloride; iron in water 48 h; Reflux;
参考文献
De Fatima Pereira, Maria; Thiery, Valerie
Organic Letters, 2012 , vol. 14, # 18 p. 4754 - 4757,4
反应条件
potassium phosphate; copper(l) iodide; (-)-sparteine in 1-methyl-pyrrolidin-2-one T=130°C; 48 h;
参考文献
Reeves, Jonathan T.; Fandrick, Daniel R.; Tan, Zhulin; Song, Jinhua J.; Lee, Heewon; Yee, Nathan K.; Senanayake, Chris H.
Journal of Organic Chemistry, 2010 , vol. 75, # 3 p. 992 - 994
反应条件
1: 70 percent / 216 h / Heating 2: 78 percent / triethylamine; phosphoryl chloride / tetrahydrofuran / 0.2 h / 0 °C 3: 97 percent / BF3*Et2O / CH2Cl2 / 0.33 h / 0 °C View Scheme
参考文献
Kobayashi, Kazuhiro; Matoba, Takeshi; Irisawa, Susumu; Matsumoto, Takashi; Morikawa, Osamu; Konishi, Hisatoshi
Chemistry Letters, 1998 , # 6 p. 551 - 552
反应条件
1: 78 percent / triethylamine; phosphoryl chloride / tetrahydrofuran / 0.2 h / 0 °C 2: 97 percent / BF3*Et2O / CH2Cl2 / 0.33 h / 0 °C View Scheme
参考文献
Kobayashi, Kazuhiro; Matoba, Takeshi; Irisawa, Susumu; Matsumoto, Takashi; Morikawa, Osamu; Konishi, Hisatoshi
Chemistry Letters, 1998 , # 6 p. 551 - 552
反应条件
1: With [RhI2(p-cymene)]2 in tetrahydrofuran
T=20°C; 0.166667 h; Glovebox;
2: With hydrogen in tetrahydrofuran
T=20°C; P=10343.2 Torr; 16 h; Autoclave;
参考文献
Chen, Zhang-Pei; Chen, Mu-Wang; Guo, Ran-Ning; Zhou, Yong-Gui
Organic Letters, 2014 , vol. 16, # 5 p. 1406 - 1409
