4-(1H-吡咯-1-基)苯甲醛合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1.5 h;
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
nickel monoaluminide in pyridine; ethyl acetate
参考文献
Merck and Co., Inc.
Patent: US4207329 A1, 1980 ;
反应条件
pyridinium chlorochromate in dichloromethane 1.5 h; Ambient temperature;
参考文献
Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
反应条件
1: 1-(para-bromophenyl)-1H-pyrrole With n-butyllithium in tetrahydrofuran; hexane T=-70°C; 2 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-70 - 20°C; 4 h;
参考文献
Nakazaki, Jotaro; Chung, InGwon; Matsushita, Michio M.; Sugawara, Tadashi; Watanabe, Ryoji; Izuoka, Akira; Kawada, Yuzo
Journal of Materials Chemistry, 2003 , vol. 13, # 5 p. 1011 - 1022
反应条件
1: 46 percent / 1-(3-(dimethylamino)propyl)-3-ethylcarbodiimide / CH2Cl2 / 18 h / Ambient temperature 2: 100 percent / LiAlH4 / tetrahydrofuran / 1.5 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 13 p. 2390 - 2410
反应条件
1: 92 percent / NaBH4, CaCl2 / tetrahydrofuran / Ambient temperature 2: 87 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 27, # 3 p. 219 - 228
反应条件
potassium carbonate in dimethyl sulfoxide 0.25 h; ultrasound;
参考文献
Tetrahedron, , vol. 57, # 22 p. 4781 - 4785
反应条件
1.1: 85 percent / acetic acid / 1 h / Heating 2.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -70 °C 2.2: 80 percent / tetrahydrofuran; hexane / 4 h / -70 - 20 °C View Scheme
参考文献
Journal of Materials Chemistry, , vol. 13, # 5 p. 1011 - 1022
反应条件
Paal-Knorr pyrrole synthesis;
参考文献
Synthesis, , # 6 art. no. M06008SS, p. 980 - 984
