N-甲基-N-(1-苯基丙烷-2-基)丙-2-炔-1-胺合成路线 （共 20 条）
反应条件
sodium carbonate 1 h;
参考文献
International Journal of Pharmaceutics, , vol. 416, # 2 p. 453 - 460
反应条件
1: 95 percent / triethylamine / CH2Cl2 / 1 h / 0 °C 2: 92 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating 3: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1: 70 percent / Raney-Nickel; AcOH; hydrogen / methanol / 16 h / 20 °C / 3102.97 Torr 2: 0.1 g / triethylamine / CH2Cl2 / 1 h / 0 °C 3: triethylamine / CH2Cl2 / 1 h / 0 °C 4: LiAlH4 / tetrahydrofuran / 4 h / Heating 5: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1: 0.1 g / triethylamine / CH2Cl2 / 1 h / 0 °C 2: triethylamine / CH2Cl2 / 1 h / 0 °C 3: LiAlH4 / tetrahydrofuran / 4 h / Heating 4: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1: triethylamine / CH2Cl2 / 1 h / 0 °C 2: LiAlH4 / tetrahydrofuran / 4 h / Heating 3: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1: LiAlH4 / tetrahydrofuran / 4 h / Heating 2: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1: 92 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating 2: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1.1: 85 percent / triethylamine; thionyl chloride / 0.75 h / 0 °C 2.1: sodium azide / dimethylformamide / 6 h / 80 °C 2.2: PPh3 / acetonitrile / 6 h / Heating 2.3: ammonium formate / Pd/C / methanol / 4 h / Heating 3.1: aq. K2CO3 / CH2Cl2 / 0.75 h 4.1: 0.215 g / LiAlH4 / tetrahydrofuran / 2 h / Heating 5.1: K2CO3 / acetonitrile / 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 15, # 19 p. 3111 - 3116
反应条件
1.1: sodium azide / dimethylformamide / 6 h / 80 °C 1.2: PPh3 / acetonitrile / 6 h / Heating 1.3: ammonium formate / Pd/C / methanol / 4 h / Heating 2.1: aq. K2CO3 / CH2Cl2 / 0.75 h 3.1: 0.215 g / LiAlH4 / tetrahydrofuran / 2 h / Heating 4.1: K2CO3 / acetonitrile / 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 15, # 19 p. 3111 - 3116
反应条件
2: 82 percent / K2CO3, Bu4NBr / toluene; H2O / 24 h / Ambient temperature View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 126, # 2 p. 107 - 109
