2-[2,4,6-三碘-3-[N-甲基(乙酰基)氨基]苯基]丁酸合成路线 （共 8 条）
反应条件
1: NaBH4 / methanol 2: aq. HBr / acetic acid 3: ethanol 4: aq. H2SO4 5: H2 / Raney-Ni / ethanol 6: KICl2, aq. HCl 7: (i) H2SO4, (ii) aq. NaOH 8: aq. KOH / acetone View Scheme
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
反应条件
1: aq. HBr / acetic acid 2: ethanol 3: aq. H2SO4 4: H2 / Raney-Ni / ethanol 5: KICl2, aq. HCl 6: (i) H2SO4, (ii) aq. NaOH 7: aq. KOH / acetone View Scheme
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
反应条件
1: ethanol 2: aq. H2SO4 3: H2 / Raney-Ni / ethanol 4: KICl2, aq. HCl 5: (i) H2SO4, (ii) aq. NaOH 6: aq. KOH / acetone View Scheme
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
反应条件
1: aq. H2SO4 2: H2 / Raney-Ni / ethanol 3: KICl2, aq. HCl 4: (i) H2SO4, (ii) aq. NaOH 5: aq. KOH / acetone View Scheme
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
反应条件
1: H2 / Raney-Ni / ethanol 2: KICl2, aq. HCl 3: (i) H2SO4, (ii) aq. NaOH 4: aq. KOH / acetone View Scheme
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
反应条件
1: KICl2, aq. HCl 2: (i) H2SO4, (ii) aq. NaOH 3: aq. KOH / acetone View Scheme
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
反应条件
1: (i) H2SO4, (ii) aq. NaOH 2: aq. KOH / acetone View Scheme
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
反应条件
potassium hydroxide in acetone
参考文献
Felder; Pitre; Fumagalli; Lorenzotti
Journal of medicinal chemistry, 1970 , vol. 13, # 3 p. 559 - 561
