1-(3-氨基丙基)吡咯烷合成路线 （共 12 条）
反应条件
lithium aluminium tetrahydride in diethyl ether 5.5 h; Heating;
参考文献
Valenta, Vladimir; Vlkova, Marie; Holubek, Jiri; Metysova, Jirina; Protiva, Miroslav
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 7 p. 1979 - 1994
反应条件
in tetrahydrofuran; ethanol; water
参考文献
Farmaco, Edizione Scientifica, , vol. 13, p. 261,282
反应条件
hydrogenchloride; sodium tetrahydroborate in water T=23°C; 16 h; pH 7;
参考文献
Brandaenge, Svante; Eriksson, Lars-Hakan; Rodriguez, Benito
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1984 , vol. 38, # 6 p. 526 - 528
反应条件
1: 1.) LiAlH4, 2.) 0.1 M NaOH / 1.) diethyl ether, reflux, 2 h, 2.) 25 deg C, 10 min 2: 0.20 g / aq. HCl, NaBH4 / H2O / 16 h / 23 °C / pH 7 View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 38, # 6 p. 526 - 528
反应条件
1: toluene 2: aqueous hydrochloric acid View Scheme
参考文献
Farmaco, Edizione Scientifica, , vol. 13, p. 261,282
反应条件
T=100°C; Erhitzen im Rohr; Kochen des Reaktionsprodukts erst mit verd. Natronlauge, dann mit Salzsaeure;
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 161, p. 67
反应条件
hydrazine in ethanol 3 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 13 p. 2131 - 2135
反应条件
1: Heating 2: LiAlH4 / diethyl ether / 3 h View Scheme
参考文献
Badger; Schwartz; Picker; Dorman; Bradley; Cheeseman; DiMartino; Hanna; Mirabelli
Journal of Medicinal Chemistry, 1990 , vol. 33, # 11 p. 2963 - 2970
反应条件
1: 97 percent / Heating
2: 100 percent / LiAlH4 / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
De Costa; Radesca; Di Paolo; Bowen
Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 38 - 47
