N,N-二乙基-2-氯乙酰胺合成路线 （共 70 条）
反应条件
sodium in ethanol 4 h; Heating;
参考文献
Dogruer, Deniz Songuel; Uenlue, Serdar; Sahin, Mustafa Fethi; Yesilada, Erdem
Farmaco, 1998 , vol. 53, # 1 p. 80 - 84
反应条件
triethylamine in ethanol 20 h; Heating;
参考文献
Tsukube, Hiroshi; Adachi, Hayamitsu; Morosawa, Shiro
Journal of Organic Chemistry, 1991 , vol. 56, # 25 p. 7102 - 7108
反应条件
(i) Na, (ii) /BRN= 605866/; Multistep reaction;
参考文献
Short,J.H. et al.
J. Med. Chem., 1965 , vol. 8, p. 223 - 230
反应条件
hydrogenchloride; Co(PMe3)4
1.) THF, r.t., 15 min, 2.) Et2O; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Orsini; Pelizzoni; Pulici
Journal of Organic Chemistry, 1994 , vol. 59, # 1 p. 1 - 3
反应条件
1.1: lithium diisopropylamide / tetrahydrofuran / 0.17 h / -78 °C
1.2: tetrahydrofuran / 1 h / -78 °C
2.1: sodium hydride / CH2Cl2 / 2.5 h / 25 °C
3.1: SmI2; MeOH / tetrahydrofuran / 0.5 h / 25 °C
View Scheme
参考文献
Concellon, Jose M.; Bardales, Eva
Journal of Organic Chemistry, 2003 , vol. 68, # 24 p. 9492 - 9495
参考文献
Speziale,A.J.; Frazier,H.W.
Journal of Organic Chemistry, 1961 , vol. 26, p. 3176 - 3183
反应条件
nitronium tetrafluoroborate
T=30°C; var. ratio of reactants, var. temperatures; Product distribution;
参考文献
Andreev, S. A.; Lebedev, B. A.; Tselinskii, I. V.; Shokhor, I. N.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 7 p. 1159 - 1166
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 7 p. 1353 - 1360
反应条件
sodium hydroxide; Aliquatreg; 336 in dichloromethane
T=10 - 15°C; 2.5 h; Yield given;
参考文献
Kem, Kenneth M.; Nguyen, Nghi V.; Cross, Dennis J.
Journal of Organic Chemistry, 1981 , vol. 46, p. 5188 - 5192
反应条件
in N,N-dimethyl-formamide
T=120°C; 4 h;
参考文献
Schapira, Celia B.; Abasolo, Maria I.; Perillo, Isabel A.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 577 - 581
参考文献
Medved', T. Ya.; Chmutova, M. K.; Nesterova, N. P.; Koiro, O. E.; Kochetkova, N. E.; et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 9 p. 1743 - 1747
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , vol. 30, # 9 p. 2121 - 2127
