N,N-二乙基-2-氯乙酰胺合成路线 （共 70 条）
反应条件
sodium hydroxide; sodium iodide in acetonitrile T=23°C; pH=12;
参考文献
Loeser, Eric; Prasad, Kapa; Repic, Oljan
Synthetic Communications, 2002 , vol. 32, # 3 p. 403 - 409
参考文献
Am.Home Prod.Corp.
Patent: US2676188 , 1950 ;
反应条件
trichlorophosphate 1) 0 deg C 2) CHCl3, reflux; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Borse, Arvind P.; Kelkar, Shriniwas L.; Wadia, Murban S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1180 - 1181
反应条件
sodium ethanolate Heating;
参考文献
Crescenzi,E.; Marazzi-Uberti,E.
Bollettino Chimico Farmaceutico, 1965 , vol. 104, p. 105 - 110
反应条件
1: 75 percent / lithium / tetrahydrofuran / 15 h / Ambient temperature 2: 83 percent / 2 h / 90 - 100 °C 3: methanol / 3 h / Heating View Scheme
参考文献
Deleris; Dunogues; Babin; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 533 - 537
反应条件
trichlorophosphate T=0 - 70°C;
参考文献
Preobrashenskaja et al.
Chim.farm.Z., 1972 , vol. 6, # 1 p. 32,37;engl.Ausg.S.33,37
反应条件
(i) NaH, DMF, (ii) /BRN= 605866/; Multistep reaction;
参考文献
Islip; Closier; Neville
Journal of Medicinal Chemistry, 1974 , vol. 17, # 2 p. 207 - 209
参考文献
Marini-Bettolo; Cavalla
Gazzetta Chimica Italiana, 1954 , vol. 84, p. 896,905
参考文献
Sou
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1930 , vol. 191, p. 944,945
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1931 , vol. 192, p. 1462 - 1464
反应条件
trichlorophosphate 1) 0 deg C 2) CHCl3, reflux; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Borse, Arvind P.; Kelkar, Shriniwas L.; Wadia, Murban S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 1180 - 1181
