N,N-二乙基-2-氯乙酰胺合成路线 (共 70 条)
反应条件
triethylamine in dichloromethane T=0°C;
参考文献
Hilton; Motherwell; Potier; Pradet; Selwood
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 9 p. 2239 - 2242
反应条件
N-ethyl-N,N-diisopropylamine
反应条件
1: chloroacetic acid With dicyclohexyl-carbodiimide in dichloromethane T=20°C; 0.5 h; 2: diethylamine With 4-(N,N-dimethlyamino)pyridine in dichloromethane T=20°C;
参考文献
European Journal of Medicinal Chemistry, , vol. 41, # 8 p. 985 - 990
反应条件
in dichloromethane T=-25 - 20°C; 3.5 h;
参考文献
Chemistry of Natural Compounds, , vol. 48, # 6 p. 1047 - 1053
Khim. Prir. Soedin., , vol. 48, # 6 p. 924 - 929,6
参考文献
Bulletin de la Societe Chimique de France, , p. 1414,1416
反应条件
(i) nBuLi, (ii) H2O; Multistep reaction;
参考文献
Bulletin de la Societe Chimique de France, , p. 1528 - 1532
参考文献
Doklady Chemistry, , vol. 171, p. 1184 - 1187
Doklady Akademii Nauk SSSR, , vol. 171, p. 1116 - 1119
参考文献
Chemische Berichte, , vol. 76, p. 87
反应条件
potassium carbonate in butan-1-ol
参考文献
Freed,M.E. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 2378 - 2383
反应条件
1: sodium acetate / 16 h / Heating 2: sodium methoxide / methanol / 3 h View Scheme
参考文献
Starrett, John E.; Tortolani, David R.; Russell, John; Hitchcock, Michael J. M.; Whiterock, Valerie; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 12 p. 1857 - 1864