反应条件
1.1: Et3SiH; TFA / 0 - 20 °C
2.1: (COCl)2; DMF / CH2Cl2 / -10 - 20 °C
3.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -70 - -50 °C
3.2: 91 percent / tetrahydrofuran; hexane / -70 - 0 °C
4.1: NaN(SiMe3)2 / tetrahydrofuran / 1 h / -75 °C
4.2: 61 percent / tetrahydrofuran / -70 - -50 °C
5.1: 97 percent / aq. H2O2; LiOH / tetrahydrofuran / 0 - 20 °C
6.1: 99 percent / N-(dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride; i-Pr2NEt; 1-hydroxy-1,2,3-benzotriazole hydrate / CH2Cl2 / 4 - 20 °C
7.1: 80 percent / TFA / CH2Cl2 / 2 h / 20 °C
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