3,5-二氯-2-硝基苯甲酸合成路线 （共 7 条）
反应条件
sulfuric acid; nitric acid T=20°C; 2.5 h;
参考文献
IHARA CHEMICAL INDUSTRY CO., LTD
Patent: US2012/178931 A1, 2012 ;
Location in patent: Page/Page column 10 ;
反应条件
potassium permanganate
参考文献
Asinger
Monatshefte fuer Chemie, 1933 , vol. 63, p. 385,390
反应条件
1: nitric acid / 0 °C 2: aqueous potassium permanganate solution View Scheme
参考文献
Asinger
Monatshefte fuer Chemie, 1933 , vol. 63, p. 385,390
反应条件
potassium permanganate; tetrabutylammomium bromide
参考文献
Dong, Kui-Kui; Zhou, Hua-Hong; Guo, A-Rong; Chen, Tian; Wang, Yu-Liang
Asian Journal of Chemistry, 2013 , vol. 25, # 2 p. 1039 - 1042
反应条件
(i) K2S2O8, H2SO4, (ii) HNO3; Multistep reaction;
参考文献
Umio,S. et al.
Chemical and Pharmaceutical Bulletin, 1969 , vol. 17, p. 596 - 604
参考文献
Asinger
Monatshefte fuer Chemie, 1933 , vol. 63, p. 385,390
反应条件
hydrogen; rhenium; nickel in methanol T=20°C;
参考文献
VITAE PHARMACEUTICALS, INC.
Patent: WO2009/108332 A1, 2009 ;
Location in patent: Page/Page column 54 ;
WO 2009/108332 A1
