4,4-二甲基-2-咪唑并啉合成路线 （共 15 条）
反应条件
1: 94 percent / triethylamine / CH2Cl2 / 0 deg C, then warming to RT, 1 h
2: 76 percent / CH2Cl2 / Heating
3: 92 percent / NaBH4 / ethanol / 1 h / 0 °C
View Scheme
参考文献
Bieraeugel, H.; Plemp, R.; Hiemstra, H. C.; Pandit, U. K.
Tetrahedron, 1983 , vol. 39, # 23 p. 3971 - 3980
反应条件
1: 62 percent / triethylamin / CH2Cl2 / 0 deg C, then warming to RT
2: 80 percent / CH2Cl2 / 6 h / Heating
3: 1.) Mg / 1.) THF, 2.) THF, RT
View Scheme
参考文献
Bieraeugel, H.; Plemp, R.; Hiemstra, H. C.; Pandit, U. K.
Tetrahedron, 1983 , vol. 39, # 23 p. 3971 - 3980
反应条件
1: 62 percent / triethylamin / CH2Cl2 / 0 deg C, then warming to RT
2: 80 percent / CH2Cl2 / 6 h / Heating
3: 1.) Mg / 1.) THF, 2.) THF, RT
View Scheme
参考文献
Bieraeugel, H.; Plemp, R.; Hiemstra, H. C.; Pandit, U. K.
Tetrahedron, 1983 , vol. 39, # 23 p. 3971 - 3980
反应条件
1: 62 percent / triethylamin / CH2Cl2 / 0 deg C, then warming to RT
2: 80 percent / CH2Cl2 / 6 h / Heating
3: 1.) Mg / 1.) THF, 2.) THF, RT
View Scheme
参考文献
Bieraeugel, H.; Plemp, R.; Hiemstra, H. C.; Pandit, U. K.
Tetrahedron, 1983 , vol. 39, # 23 p. 3971 - 3980
反应条件
1: 62 percent / triethylamin / CH2Cl2 / 0 deg C, then warming to RT
2: 80 percent / CH2Cl2 / 6 h / Heating
3: 1.) Mg / 1.) THF, 2.) HMPT, THF, RT
View Scheme
参考文献
Bieraeugel, H.; Plemp, R.; Hiemstra, H. C.; Pandit, U. K.
Tetrahedron, 1983 , vol. 39, # 23 p. 3971 - 3980
